摘要
目的探讨术前糖化血红蛋白(glycated hemoglobin,HbA1c)水平对妇科手术患者术后手术部位感染(surgical site infection,SSI)的影响及预测价值。方法前瞻性选取2017年1月至2020年12月在石家庄市第二医院手术治疗妇科疾病患者220例作为研究对象,根据是否发生SSI进行分组,观察SSI和非SSI患HbA1c水平,采用多因素Logistic回归分析观察HbA1c对SSI的影响,采用受试者工作曲线(receiver operating curve,ROC)计算术前HbA1c预测SSI的最佳截断值。结果SSI患者糖尿病患者百分率、术前血糖、术前HbA1c均高于非SSI患者。多因素Logistic回归分析结果显示,剔除混杂因素后术前HbA1c和术前血糖均是影响SSI发生的影响因素(P<0.05)。HbA1c预测SSI的最佳截断值8.8%。结论术前HbA1c是妇科手术患者SSI的独立风险因素,HbA1c预测SSI的最佳截断值为8.8%。
Objective:To explore the impact and predictive value of preoperative glycated hemoglobin(HbAlc)levels on postoperative surgical site infection(SSI)in gynecological surgery patients.Methods;A prospective study was conducted on 220 patients with gynecological diseases who underwent surgical treatment at Shijiazhuang Second Hospital from January 2017 to December 2020.Patients were divided into groups based on the occurrence of SSI,and HbAlc levels were observed in both SSI and non SSI patients.Multivariate logistic regression analysis was used to observe the impact of HbAlc on SSL Receiver operating curve(ROC)was used to calculate the optimal cutoff value of preoperative HbAlc for predicting SSI.ResultS:The percentage of patients with diabetes,preoperative blood glucose and preoperative HbAlc in SSI patients were higher than those in non SSI patients.The results of multivariate logistic regression analysis showed that after removing confounding factors,preoperative HbAlc and preoperative blood glucose were both influencing factors on the occurrence of SSI(P<0.05).The optimal cutoff value for predicting SSI with HbAlc is 8.8%.Conclusion;Preoperative HbAlc is an independent risk factor for SSI in gynecological surgery patients,and the optimal cutoff value for predicting SSI with HbAlc is 8.8%.
作者
高伟聪
李丽
张中华
朱向辉
刘素巧
GAO Weicong;LI li;ZHANG Zhong hua;ZHU Xiang hui;LIU Su qiao(Gynecology&-Obstetrics,Shijiazhuang City Second Hospital,China,050000;clinicallaboratory,Shijiazhuang City Second Hospital,China,050000)
出处
《生命科学仪器》
2023年第3期156-159,共4页
Life Science Instruments
基金
石家庄市科学技术研究与发展指导计划项目(171461463)
关键词
妇科手术
糖尿病
糖化血红蛋白
手术部位感染
预测价值
Gynecological Surgery
Diabetes
Glycated Hemoglobin
Surgical Site Infection
Predictive Value
