摘要
目的:探讨基于“清热解毒”法运用加味四妙勇安膏治疗放射性皮炎的价值。方法纳入2022年8月-2023年6月我院100例放射性皮炎患者为研究对象,采用随机数字表法将患者分为对照组与研究组,每组50例。对照组予以常规西药治疗,研究组在对照组的基础上予以加味四妙勇安膏治疗。治疗后比较两组患者临床疗效、中医症候积分、炎症指标及皮损愈合时间。结果:治疗结束时,研究组临床治疗总有效率为90.00%,高于对照组(74.00%)(P<0.05);治疗结束时,研究组皮肤红斑、瘙痒、溃疡、红肿疼痛中医症候积分低于对照组(P<0.05);治疗结束时,研究组TNF-α、IL-6水平低于对照组(P<0.05);治疗后,1~2级皮损愈合时间较3级愈合时间短,且研究组均短于对照组(P<0.05)。结论:基于“清热解毒”法的加味四妙勇安膏治疗放射性皮炎可有效提高临床疗效,缓解中医症候症状严重程度,抑制患者炎症反应,缩短皮损愈合时间。
Objective:To explore the value of Jiawei Simiao Yong an ointment in treating radiation dermatitis based on the method of"clearing away heat and toxic materials".Methods;100 patients with radiation dermatitis in our hospital from August 2022 to June 2023 were included as the research object,and the patients were randomly divided into control group and research group,with 50 cases in each group.The control group was treated with routine western medicine,while the research group was treated with Jiawei Simiao Yong an Ointment on the basis of the control group.After treatment,the clinical efficacy.TCM symptom score,inflammation index and skin lesion healing time of the two groups were compared.Results:At the end of treatment,the total effective rate of the study group was 90.00%.which was higher than that of the control group(74.00%)(P<0.05).At the end of treatment.the scores of TCM symptoms of skin erythema,itching,ulcer,swelling and pain in the study group were lower than those in the control group(P<0.05).At the end of treatment,the levels of TNF—α and IL—6 in the study group were lower than those in the control group(P<0.05).After treatment,the healing time of grade 1~2 skin lesions was shorter than that of grade 3.and the study group was shorter than the control group(P<50.05).Conclusion;Jiawei Simiao Yong an Ointment based on the method of"clearing heat and detoxicating"can effectively improve the clinical efficacy,relieve the severity of TCM symptoms,inhibit the inflammatory reaction of patients and shorten the healing time of skin lesions.
作者
鞠齐峰
杨素清
袁锐
JU Qifeng;YANG Suqing;YANG Rui(Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang 150010,China)
出处
《生命科学仪器》
2023年第3期136-139,共4页
Life Science Instruments
关键词
放射性皮炎
加味四妙勇安膏
清热解毒
Radiodermatitis
Jiawei Simiao Yong an ointment
clear heat and detoxicate
