摘要
目的探究丁苯酞联合阿加曲班治疗急性脑梗死的临床疗效。方法选择2018年9月—2019年9月在本院住院治疗的急性脑梗死患者110例作为研究对象,随机数表法分为对照组及观察组两组,每组各55例。在常规对症治疗的基础上,对照组给予阿加曲班,观察组给予丁苯酞联合阿加曲班治疗,观察治疗后各组患者的总有效率及NIHSS、ADL评分情况。结果观察组的总有效率显著优于对照组,差异具有统计学意义(P<0.05);治疗后,两组患者NIHSS评分及ADL的改善程度显著优于治疗前,差异具有统计学意义(P<0.05);并且观察组NIHSS评分降低及ADL评分升高程度优于对照组,均具有显著差异(P<0.05)。结论丁苯酞联合阿加曲班能够有效减轻急性脑梗死患者的神经功能损伤,并可有效提升其生活自理能力,对急性脑梗死患者的治疗效果显著。
Objective To explore the clinical effect of butylphthalide combined with argatraban in the treatment of acute cerebral infarction.Methods 110 patients with acute cerebral infarction who were hospitalized in our hospital from September 2018 to September 2019 were selected as the study objects and they were randomly divided into control group and observation group,with 55 cases each group.On the basis of routine symptomatic treatment,the control group was given argatraban,and the observation group was given butylphthalide combined with argatraban.The total effective rate,NIHSS and ADL scores of each group were observed after treatment.Results The total effective rate of the observation group was significantly higher than that of the control group,the difference was statistically significant(P<0.05);the improvement degree of NIHSS score and ADL score in the two groups after treatment were significantly higher than those before treatment,the differences were statistically significant(P<0.05),and the decrease of NIHSS score and increase of ADL score in the observation group after treatment were significantly different from those in the control group(P<0.05).Conclusions Butylphthalide combined with argatraban could effectively reduce the neurological damage in patients with acute cerebral infarction,and effectively improve their ability of self-care,which has a significant therapeutic effect on patients with acute cerebral infarction.
作者
梁潇
阎保伟
LIANG Xiao(Tianjin yellow river hospital,Tianjin,150040,China)
出处
《齐齐哈尔医学院学报》
2021年第9期751-753,共3页
Journal of Qiqihar Medical University
基金
天津市科技计划重点项目(12ZCZDSY03200)
天津市卫生局科技重点攻关项目(12KG127)
关键词
急性脑梗死
丁苯酞
阿加曲班
疗效
Acute cerebral infarction
Butylphthalide
Argatraban
Efficacy
