摘要
目的分析比较胃炎胃溃疡分别应用奥美拉唑、兰索拉唑与泮托拉唑治疗的效果及安全性。方法于广西壮族自治区人民医院2017年1月—2019年3月收治的胃炎胃溃疡患者中选取150例,随机分为三组,分别给予兰索拉唑、奥美拉唑与泮托拉唑治疗,比较三组患者的临床效果和不良反应发生情况。结果奥美拉唑组治疗有效率为94.0%,泮托拉唑组为92.0%,兰索拉唑组为90.0%,组间差异无统计学意义(P>0.05)。奥美拉唑组不良反应发生率为2.0%,显著低于泮托拉唑组的14.0%和兰索拉唑组的16.0%,差异有统计学意义(P<0.05)。结论在胃炎胃溃疡治疗中奥美拉唑、兰索拉唑与泮托拉唑均具有较好疗效,但奥美拉唑的不良反应更少,安全性较高,可作为临床治疗胃炎胃溃疡的首选药物。
Objective To analyze and compare the efficacy and safety of omeprazole,lansoprazole and pantoprazole in the treatment of gastritis and gastric ulcer.Methods 150 patients with gastritis and gastric ulcer admitted to People’s Hospital of Guangxi Zhuang Autonomous Region from January 2017 to March 2019 were divided into three groups.Lansoprazole,omeprazole and pantoprazole were given respectively.The clinical effects and adverse reactions of the three groups were compared.Results The effective rate of omeprazole group,pantoprazole group and lansoprazole group was 94.0%,92.0%and 90.0%,respectively.There was no significant difference between the two groups(P>0.05).The incidence of adverse reactions in omeprazole group was 2.0%,significantly lower than that in pantoprazole group(14.0%)and lansoprazole group(16.0%)(P<0.05).Conclusion Omeprazole,lansoprazole and pantoprazole are effective in the treatment of gastritis and gastric ulcer,but Omeprazole has fewer adverse reactions and higher safety.It can be used as the first choice for the treatment of gastritis and gastric ulcer.
作者
张莉
叶溪
刘晓霞
ZHANG Li;YE Xi;LIU Xiaoxia(Department of Clinical Pharmacy,People's Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China)
出处
《中国全科医学》
CAS
北大核心
2020年第S01期158-160,共3页
Chinese General Practice
关键词
泮托拉唑
胃炎胃溃疡
奥美拉唑
临床效果
兰索拉唑
Pantoprazole
Gastritis and Gastric Ulcer
Omeprazole
Clinical Effect
Lansoprazole
