摘要
目的:结合早期先兆流产患者的凝血功能、同型半胱氨酸(Hcy)、B族维生素水平检测结果,分析各项指标与早期先兆流产发生的相关性。方法:收集我院2018年4月—2019年4月收治的74例早期先兆流产患者和同期收治的70例健康产妇作为研究对象,分别为观察组和对照组,进行凝血功能、Hcy、B族维生素等各项指标的检测,对比其差异性。结果:观察组患者的血小板计数(PLT)水平、纤维蛋白原(Fbg)水平、D-二聚体、Hcy、维生素B_(12)、叶酸与对照组比较,差异具有统计学意义(P<0.05)。在不同妊娠结局产妇中,PLT、Fbg、D-二聚体以及Hcy的检测结果显示,成功分娩者最低,难免流产者其次,稽留流产者最高。而维生素B_(12)、叶酸检测结果显示,成功分娩者最高,难免流产者其次,稽留流产者最低。结论:早期先兆流产的发生,与产妇的凝血功能、Hcy、B族维生素存在相关性,可以根据以上指标的检测结果,评估先兆流产发生风险,进而为早期防治流产提供有价值的参考。
Objective:This paper is aimed to analyze the correlation of the coagulation function,homocysteine(Hcy)and B vitamins in patients with early threatened abortion.Methods:A total of 74 patients with early threatened abortion admitted to our hospital from April 2018 to April 2019 and 70 healthy puerperas admitted in the same period were selected as the research objects,and divided them into the observation group and the control group.The coagulation function,Hcy,B vitamins and other indicators were detected,and the differences were compared.Results:The levels of platelet count(PLT),fibrinogen(Fbg),D-dimer,Hcy,vitamin B_(12)and folic acid in the observation group were significantly different from those in the control group(P<0.05).Among women with different pregnancy outcomes,PLT,Fbg,D-dimer and Hcy detection results showed that successful delivery was the lowest,inevitable abortion was the second,and missed abortion was the highest.The results of vitamin B_(12)and folic acid tests showed that successful delivery was the highest,followed by inevitable abortion but missed abortion was the lowest.Conclusion:The occurrence of early threatened abortion is correlated with maternal coagulation function,Hcy and B vitamins.The risk of threatened abortion can be evaluated according to the detection results of the above indicators,which provides valuable reference for early prevention and treatment.
作者
张颖
Zhang Ying(Qinghai Red Cross Hospital,810000)
出处
《青海医药杂志》
CAS
2022年第7期1-4,共4页
Qinghai Medical Journal
