摘要
目的观察补肾地龟汤治疗脾肾气虚型慢性肾炎蛋白尿的效果。方法选取2016年7月-2018年8月四川省眉山市中医医院肾病科收治的脾肾气虚型慢性肾炎蛋白尿患者68例,随机分为观察组和对照组各34例。观察组采取补肾地龟汤治疗,对照组采用盐酸贝那普利片治疗。比较2组临床疗效、治疗前后24 h尿蛋白定量及中医症候积分。结果观察组总有效率为88.24%高于对照组的70.59%(χ2=9.47,P<0.05)。治疗后2组患者24 h尿蛋白定量均低于治疗前,且观察组低于对照组(P<0.05);治疗后观察组患者各项中医症候积分均低于治疗前,差异均有统计学意义(P<0.05),而对照组患者各项中医症候积分与治疗前比较差异均无统计学意义(P>0.05)。结论补肾地龟汤治疗脾肾气虚型慢性肾炎蛋白尿能有效改善患者的临床症状,改善蛋白尿水平,效果较好,值得广泛推广。
Objective To observe the effect of Bushen Digui decoction on proteinuria of spleen-kidney qi deficiency type chronic nephritis.Methods From July 2016 to August 2018,68 patients with proteinuria due to spleen-kidney qi deficiency type chronic nephritis were selected from the Nephrology Department of Meishan Hospital of Traditional Chinese Medicine in Sichuan Province.They were randomly divided into observation group and control group,each of 34 cases.The observation group was treated with Bushen Digui decoction,the control group was treated with benazepril hydrochloride tablets.The clinical efficacy,24 h urine protein before and after treatment and TCM symptom scores of the two groups were compared.Results The total effective rate in the observation group was 88.24%higher than 70.59%in the control group(χ2=9.47,P<0.05).After treatment,the 24 h urine protein quantity of the patients in both groups was lower than that before treatment,and that in the observation group was lower than that in the control group(P<0.05);After treatment,TCM symptom scores of patients in the observation group were lower than those before treatment,the difference were statistically significant(P<0.05),while TCM symptom scores of patients in the control group were not statistically significant(P>0.05).Conclusion Bushen Digui decoction can effectively improve the clinical symptoms and proteinuria level of patients with chronic nephritis proteinuria of spleen-kidney qi deficiency type,with good effect,and is worthy of wide promotion.
作者
王燕涛
徐芳
WANG Yantao(Department of Nephrology,Meishan Traditional Chinese Medicine Hospital,Sichuan Province,Meishan 620010,China)
出处
《临床合理用药杂志》
2020年第4期27-28,30,共3页
Chinese Journal of Clinical Rational Drug Use
关键词
慢性肾炎
蛋白尿
补肾地龟汤
Chronic nephritis
Proteinuria
Bushen Digui decoction
