摘要
目的比较奥氮平与氨磺必利治疗精神分裂症的临床效果。方法选择医院84例精神分裂症患者,随机分为A、B两组。A组予以奥氮平治疗,B组予以氨磺必利治疗。对比两组治疗效果及不良反应发生状况。结果B组治疗总有效率与A组相比,无明显差异(P>0.05);B组嗜睡、泌乳与月经改变、体质量增加发生率分别为2.38%、7.14%、2.38%,明显低于A组的19.05%、23.81%、21.43%,两组之间存在显著差异(P<0.05)。结论在治疗精神分裂症方面,奥氮平和氨磺必利均可达到较好效果,但相较于奥氮平,氨磺必利的不良反应较小。
Objective To compare the clinical effects of olanzapine and amisapride in the treatment of schizophrenia.Methods Eighty-four patients with schizophrenia in our hospital were randomly divided into two groups:group A was treated with olanzapine and group B was treated with azepripine.The therapeutic effect and adverse reactions were compared between the two groups.Results There was no significant difference in the total effective rate between group B and group A(P>0.05).The incidence of drowsiness,lactation and menstrual changes,and weight gain in group B were 2.38%,7.14%,and 2.38%,respectively.There were 19.05%,23.81%,and 21.43%in group A,and there was a significant difference between the two groups(P<0.05).Conclusion Olanzapine and amisapride can achieve better results in the treatment of schizophrenia,but the adverse reactions of olanzapine are less than olanzapine.
作者
赵影
ZHAO Ying(Psychiatry Department,Changchun Sixth Hospital,Changchun Jilin 130000,China)
出处
《中国卫生标准管理》
2020年第3期82-83,共2页
China Health Standard Management
