摘要
目的探讨壳聚糖抗菌成膜喷剂在鼻咽癌患者经外周静脉置入中心静脉导管(PICC)置管部位接触性皮炎治疗中的应用效果。方法选取2020-05至2022-04联勤保障部队第909医院因置入PICC所致接触性皮炎的94例鼻咽癌患者为研究对象,其中2020-05至2021-04的46例患者为对照组,2021-05至2022-04的48例患者为观察组。对照组采用地塞米松注射液外涂联合3M透明敷料行PICC换药,观察组采用喷涂壳聚糖抗菌成膜喷剂联合3M透明敷料行PICC换药。对比观察两组患者临床疗效、并发症的发生率、愈合时间、换药次数、患者的自付费用及满意度情况。结果观察组治疗第1周、第2周总有效率(95.83%,100%)均显著高于对照组治疗总有效率(73.91%,89.13%)(P<0.05),观察组愈合时间[(10.43±0.52)d]、换药次数[(3.30±0.69)次]显著短于或少于对照组愈合时间[(18.15±0.33)d]、换药次数[(5.67±0.96)次](P<0.05),观察组患者满意度得分(8.71±0.82)显著高于对照组患者满意度得分(5.67±0.96)(P<0.05),两组患者在导管移位率、脱管率及患者自付费用三方面无明显区别,差异无统计学意义(P>0.05)。结论壳聚糖抗菌成膜喷剂治疗鼻咽癌同步放化疗患者PICC置管部位接触性皮炎效果明显,可减少换药次数,减轻护理工作量,降低局部感染率,提高患者满意度。
Objective To investigate the application effect of chitosan antibacterial film-forming spray in the treatment of PICC contact dermatitis in patients with nasopharyngeal carcinoma.Methods A total of 94 patients with nasopharyngeal carcinoma and PICC-induced contact dermatitis in the 909th Hospital of PLA Joint Logistics Support Force from May 2020 to April 2022 were selected as intervention subjects.According to time nodes,46 patients from May 2020 to April 2021 were selected as control group,and 48 patients from May 2021 to April 2022 were selected as observation group.The control group was given dexamethasone injection external coating combined with 3M transparent dressing for PICC dressing change,while the observation group was given chitosan antibacterial film forming spray combined with 3M transparent dressing for PICC dressing change.The clinical efficacy,incidence of complications,healing time,times of dressing change,out-of-pocket costs and satisfaction of patients in the two groups were compared.Results The total effective rate(95.83%,100%)in the first and second weeks of treatment in the observation group was significantly higher than that in the control group(73.91%,89.13%)(P<0.05).Healing time[(10.43±0.52)d]and dressing change times(3.30±0.69)in observation group were significantly lower than those in control group[(18.15±0.33)d;(5.67±0.96)](P<0.05).The satisfaction score of observation group(8.71±0.82)was significantly higher than that of control group(5.67±0.96)(P<0.05),and there was no significant difference in catheter displacement rate,catheter removal rate or out-of-pocket costs between the two groups(P>0.05).Conclusions Chitosan antibacterial film spray is effective in the treatment of PICC catheterization contact dermatitis in patients with nasopharyngeal carcinoma with concurrent radiotherapy and chemotherapy,which can reduce the number of dressing changes,reduce nursing workload,reduce local infection rate and improve patient satisfaction.
作者
罗晓华
郑艺君
王丽红
林丹凤
张红梅
刘志慧
LUO Xiaohua;ZHENG Yijun;WANG Lihong;LIN Danfeng;ZHANG Hongmei;LIU Zhihui(Department of Oncology,the 909th Hospital of PLA Joint Logistics Support Force/Dongnan Hospital of Xiamen University,Zhangzhou 363000,China;Department of Nursing,the 909th Hospital of PLA Joint Logistics Support Force/Dongnan Hospital of Xiamen University,Zhangzhou 363000,China)
出处
《武警医学》
CAS
2024年第2期125-129,共5页
Medical Journal of the Chinese People's Armed Police Force
基金
福建省自然科学基金(2020J011124)
