摘要
原发性膀胱少见恶性肿瘤侵袭性强,确诊有赖于病理检查及免疫组化,根治性膀胱切除术是其主要手术治疗方式。临床表现和影像学检查无特异性,难以早期诊断,且早期易出现转移,预后差,联合放化疗或可提高其生存率。本文报道了5例原发性膀胱恶性肿瘤患者,女性4例,男性1例,年龄76~84岁,病程3天至5年不等,腺癌及神经内分泌癌各2例,腺泡腺癌1例,复发1例,肉眼血尿5例,肿瘤大小介于20~60mm,4例患者行经尿道膀胱肿瘤等离子切除术,3例行腹腔镜根治性膀胱切除+双侧输尿管皮肤造口术。术后1例失访,3例远处转移。
Primary rare bladder malignant cancer is a aggressive malignancy,and definite diagnosis relies upon pathological examination.Radical cystectomy is the primary surgical treatment.As the clinical manifestations and radiographic findings of bladder rare malignancy cancer are nonspecific,with easy metastasis and poor prognosis.Early diagnosis is difficult.Adjuvant interferon-based chemoradiation improves long-term survival.A total of 5 patients(4 female,1 male)were reported,the age range was 76-84 and course of disease ranged from 3 days to 5 years.There were 2 adenocarcinoma,2 neuroendocrine cancer and 1 acinar adenocarcinoma,with 1 recurrence and 5 gross hematuria.The tumor size ranged between 20-60mm.4 patients underwent transurethral resection of bladder tumor and 3 patients underwent laparoscopic radical cystectomy and urinary diversion with double-barrel ureterocutaneostomy.1 patient was lost to follow-up and 3 patients distant metastasis during follow-up.
作者
刘良
岳霄
肖宇
倪海鑫
苑海波
李鼎
李传贵
赵琛
王元元
王建卫
殷晓松
王强
Liu Liang;Yue Xiao;Xiao Yu;Ni Haixin;Yuan Haibo;Li Ding;Li CHuangui;Zhao Chen;Wang Yuanyuan;Wang Jianwei;Yin Xiaosong;Wang Qiang(Department of Urology,Baoding No.1 Central Hospital,Baoding 071000,China;Prostate&Andrology Key Laboratory of Baoding,Baoding 071000,China;Psychosomatic Medical Center,the Fourth People's Hospital of Chengdu,Chengdu 610036,China;Psychosomatic Medical Center,the Clinical Hospital of Chengdu Brain Science Institute,MOE Key Lab for Neuroinformation,University of Electronic Science and Technology of China,Chengdu 610036,China)
出处
《微创泌尿外科杂志》
2023年第2期126-133,共8页
Journal of Minimally Invasive Urology
关键词
膀胱肿瘤
神经内分泌癌
腺癌
诊断
根治性膀胱切除术
urinary bladder neoplasms
carcinoma,neuroendocrine
adenocarcinoma
diagnosis
radical cystectomy
