摘要
目的:探讨穴位埋线疗法联合中药治疗慢性荨麻疹的疗效及对血清IL-4、IFN-γ以及IgE水平的影响。方法:选取慢性荨麻疹患者60例,按照随机数表法分为两组,各30例。对照组给予中药治疗,治疗组给予中药联合穴位埋线治疗。两组均治疗28 d后统计临床疗效,并比较两组治疗前后荨麻疹症状评分及IgE、血清IL-4、IFN-γ的水平。结果:治疗组症状改善明显优于对照组,差异有统计学意义(P<0.05)。治疗后两组IFN-γ水平升高,IL-4、IgE水平均降低,治疗前后组内比较差异有统计学意义(P<0.05);治疗后治疗组FN-γ水平升高,IL-4、IgE水平降低明显,与对照组比较差异有统计学意义(P<0.05)。结论:穴位埋线联合中药治疗慢性荨麻疹疗效确切,并能改善临床症状及降低血清IL-4、IgE水平,提高IFN-γ水平。
Objective:To explore the efficacy of acupoint catgut embedding therapy combined with traditional Chinese medicine in the treatment of chronic urticaria and its effect on serum IL-4,IFN-γand IgE level.Methods:60 patients with chronic urticaria were randomly divided into two groups with 30 patients in each group.The control group was treated with traditional Chinese medicine,and the treatment group was treated with traditional Chinese medicine combined with acupoint catgut embedding.After 28 days of treatment,the clinical efficacy of the two groups was counted,and the symptom score of urticaria and the levels of IgE,serum pro-IL-4 and IFN-γwere compared between the two groups before and after treatment.Results:The improvement of symptoms in the treatment group was significantly better than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the level of IFN-γactivity increased and the levels of IL-4 and IgE decreased in the two groups,and there was significant difference between the two groups before and after treatment.After treatment,the level of IFN-γincreased and the level of IL-4 and IgE decreased significantly in the treatment group(P<0.05).Conclusion:Acupoint catgut embedding combined with traditional Chinese medicine is effective in the treatment of chronic urticaria,and can improve clinical symptoms,reduce the level of serum IL-4 and IgE,and increase the level of IFN-γ.
作者
李振花
刘哲
宋荣强
张奕奕
王慧凯
李鹏
纪俊青
吴瑞雪
王树燕
李心盈
LI Zhen-hua;LIU Zhe;SONG Rong-qiang;ZHANG Yi-yi;WANG Hui-kai;LI Peng;JI Jun-qing;WU Rui-xue;WANG Shu-yan;LI Xin-ying(Affiliated Hospital of Binzhou Medical College,Binzhou 256603,China;Binzhou People's Hospital,Binzhou 256603,China;Binzhou Traditional Chinese Medicine Hospital,Binzhou 256603,China;Changchun University of Traditional Chinese Medicine,Changchun 130117,China)
出处
《内蒙古中医药》
2023年第1期106-108,共3页
Inner Mongolia Journal of Traditional Chinese Medicine
基金
山东省“十三五”中医药重点专科(ZDZK2016SJZY01)
关键词
慢性荨麻疹
穴位埋线
疗效观察
Chronic urticaria
Acupoint catgut embedding
Curative effect observation
