摘要
目的:探讨经直肠(TRUSB)途径与经会阴(TPB)途径前列腺穿刺对临床显著性前列腺癌(csPCa)和临床非显著性前列腺癌(insPCa)检出率的比较。方法:从2022年1月至2023年1月进行了一项前瞻性、随机的临床研究,纳入前列腺穿刺患者279例,其中TRUSB组135例,TPB组144例,比较两种穿刺途径对csPCa和insPCa的检出率。结果:TPB组前列腺癌(PCa)的检出率高于TRUSB组(37.50%vs 28.15%),差异有统计学意义(P=0.026)。TRUSB组检出6例(4.45%)insPCa和32例(23.70%)csPCa,TPB组检出10例(6.94%)insPCa和44例(30.56%)csPCa,两组对insPCa和csPCa检出率之间比较未见统计学差异(P>0.05)。不同年龄、PSA浓度和前列腺体积之间csPCa的检出率TRUSB组和TPB组无统计学差异(P>0.05)。TRUSB组和TPB组穿刺针数阳性率分别为(12.48±2.39)%和(16.44±2.86)%,差异未见统计学意义(P>0.05)。两组的尿潴留、尿道感染、血尿及直肠出血等并发症之间未见统计学差异(P均>0.05)。结论:TPB途径PCa的检出率高于TRUSB途径,但两种穿刺途径对csPCa和insPCa的检出率未见差异。
Objective:To compare transperineal prostate biopsy(TPB)with transrectal ultrasound-guided prostate biopsy(TRUSB)in detection of clinically significant prostate cancer(csPCa)and insignificant PCa(insPCa).Methods:We conducted a prospective randomized clinical study on 279 patients receiving TPB(n=144)or TRUSB(n=135)from January 2022 to January 2023,and compared the detection rates of csPCa and insPCa between the two groups.Results:The detection rate of PCa was significantly higher in the TPB than in the TRUSB group(37.50%vs 28.15%,P=0.026).There were no statistically significant differences between the TPB and TRUSB groups in the detection rates of insPCa(6.94%[n=10]vs 4.45%[n=6],P>0.05)and csPCa(30.56%[n=44]vs 23.70%[n=32],P>0.05),nor in the detection rate of csPCa between different groups of age,PSA concentration and prostate volume(P>0.05).No statistically significant differences were observed between the TPB and TRUSB groups either in the positive rate of biopsy punctures([16.44±2.86]%vs[12.48±2.39]%,P>0.05)or in the biopsy-related complications of urinary retention,urinary tract infection,hematuria and rectal bleeding(P>0.05).Conclusion:TPB is more effective than TRUSB in detection of PCa,but there is no statistically significant difference between the two approaches in the detection rates of csPCa and insPCa.
作者
刘卫勇
王涛
马丹丹
王朋
LIU Wei-yong;WANG Tao;MA Dan-dan;WANG Peng(Department of Ultrasound,Anhui Provincial Hospital/The First Hospital Affiliated to University of Science and Technology of China,Hefei,Anhui 230001,China;Department of Radiology,Anhui Provincial Hospital/The First Hospital Affiliated to University of Science and Technology of China,Hefei,Anhui 230001,China)
出处
《中华男科学杂志》
CAS
CSCD
2024年第1期26-31,共6页
National Journal of Andrology
基金
安徽省重点研究与开发计划项目(201904a07020095)
关键词
超声
前列腺穿刺
临床显著性前列腺癌
临床非显著性前列腺癌
ultrasound
prostate biopsy
clinically significant prostate cancer
clinically insignificant prostate cancer
