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银川地区TPOAb阳性对妊娠早期妇女孕期及妊娠结局的影响

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摘要 目的:探讨银川地区TPOAb阳性对妊娠早期妇女孕期及妊娠结局的影响。方法:资料来源于2014年2月到2018年2月间银川市妇幼保健院妇产科门诊的妊娠早期妇女1000例,抽取各组妊娠早期肘静脉血,检测TSH,TPOAb,FT3,FT4,其中甲状腺功能正常但TPOAb阳性65例(A组),TPOAb阳性合并TSH升高65例(B组),1000人中抽取TPOAb阴性、FT4、TSH在正常范围的健康体检者65例(C组),总共三组作为研究对象,其中B组接受优甲乐干预。记录各组孕妇早、中、晚孕期FT4、TSH水平和妊娠结局及并发症情况,进行对比分析。结果:(1)三组孕妇早、中、晚孕期FT4、TSH水平存在统计学差异(P<0.01);(2)各组孕妇妊娠事件发生率A组>B组(P<0.05),但B、C组无明显差异(P>0.05)。结论:妊娠早期妇女TPOAb阳性与其孕期及妊娠结局有密切的相关性,有必要为妊娠早期女性开展甲状腺功能筛查以及为临床或亚临床甲状腺功能异常孕妇采取干预治疗。
作者 史宁芳
出处 《中国农村卫生》 2019年第22期42-42,共1页
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