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实验动物北树鼩滇西亚种部分生理常值的研究分析

Study on some physiological constants of experimental animal North tree shrew of western Yunnan subspecies
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摘要 树鼩在2000年国家林业局将其列为《国家保护的、有益的或者有重要经济、科学研究价值的陆生野生动物名录》中,并于最近几年在医学上广泛应用的实验动物之一。已证实树鼩具有与人高度相似脑神经和视觉神经,同时,是有文献记载除了黑猩猩之外唯一一种动物能感染上人的乙型肝炎病毒的动物。本文宗旨是为建立人工饲养树鼩的生理正常值范围,用于筛选合格实验动物,为诊断树鼩疾病及应用研究提供基础资料。实验对象为人工饲养繁育30只成年北树鼩滇西亚种(雄性树鼩21只,雌性鼩9只),通过生理常值指标测定初步建立了北树鼩滇西亚种生理常值指标参数;北树鼩滇西亚种的不同性别的对比常值参数;北树鼩滇西亚种血液部分生理常值与恒河猴、大白鼠、人参考值对比。结果显示,不同性别北树鼩滇西亚种生理常值指标值,发现呼吸、血沉(24小时)、血红蛋白、嗜中性分叶核白细胞、差异性显著(P<0.05),白细胞计数差异极显著(P<0.01),其余11项指标值均无统计学差异。树鼩生理指标的检测结果某些数值显示与恒河猴、大白鼠、人有一定的差异(如体温、呼吸、心率高于恒河猴、大鼠、人参考值)。 In 2000,the State Forestry Administration listed tree shrew as one of the experimental animals in the list of terrestrial wild animals protected by the state,beneficial or of important economic and scientific research value,and it has been widely used in medicine in recent years.It has been confirmed that tree shrews have highly similar brain and visual nerves to humans.At the same time,it is documented that the only animal other than chimpanzees can be infected with human hepatitis B virus.The purpose of this paper is to establish the physiological normal range of artificially raised tree shrews,to screen qualified experimental animals,and to provide basic data for the diagnosis and application of tree shrews.In this experiment,30 adult western Yunnan subspecies(21 male shrews and 9 female shrews)were artificially raised and bred.The physiological constant index parameters of Western Yunnan subspecies were preliminarily established through the determination of physiological constant indexes;comparative constant parameters of different genders of Western Yunnan subspecies tree shrews;comparison of some physiological constants of blood in western Yunnan subspecies tree shrews with those of rhesus monkeys,rats and ginseng.The results showed that there were significant differences in respiration,erythrocyte sedimentation rate(24 hours),hemoglobin,neutrophilic lobular nucleus leukocytes and leukocyte count between different genders of Western Yunnan subspecies tree shrews(P<0.05),and there was no significant difference in the other 11 indexes(P<0.01).Some values of physiological indexes of tree shrews show certain differences with rhesus monkeys,rats and humans(for example,body temperature,respiration and heart rate are higher than those of rhesus monkeys,rats and ginseng).
作者 陆琳 文明 金钱荣 张卫卫 郭成裕 LU Lin;WEN Ming;JIN Qian rong;ZHANG Weiwei;GUO Chenyu(Yunnan Forest Nature Center,Kunming 650224;Shandong Leling Forestry Bureau,Leling,253600;Yunnan Agricultural University,Kunming 650201)
出处 《林业建设》 2022年第3期40-44,共5页 Forestry Construction
关键词 北树鼩滇西亚种 生理常值 实验动物 Western Yunnan subspecies tree shrew physiological constant experimental animal
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