摘要
目的研究自拟健脾益肾方治疗慢性肾衰竭(CRF)脾肾亏虚证48例临床价值。方法将48例慢性肾衰患脾肾亏虚证者随机分为观察组25例,对照组23例,观察组和对照组均给予西医基础治疗,观察组加用自拟健脾益肾方治疗,观察比较两组患者的临床疗效。结果治疗后,两组临床有效率分别为88.00%和60.87%,差异存在统计学意义(P<0.05);治疗后,两组中医证候积分均明显较治疗前降低(P<0.05),且观察组低于对照组(P<0.05);治疗后,两组患者的血尿素氮(BUN)、血肌酐(SCr)水平较治疗前均明显降低,估算肾小球滤过率(eGFR)水平均明显升高(P<0.05),且观察组优于对照组(P<0.05)。结论自拟健脾益肾方在治疗CRF方面有较为确切的临床效果,可减缓临床症状,改善机体肾功能,加速患者恢复进程。
Objective To study the clinical value of Self-made Jianpi Yishen Formula(自拟健脾益肾方)in the treatment of chronic renal failure(CRF)of spleen-kidney deficiency syndrome.Methods Forty-eight patients with CRF of spleen-kidney deficiency syndrome were randomLy divided into 25 cases in the observation group and 23 cases in the control group.The observation group and the control group were given basic western medicine treatment,and the observation group was additionally treated with Self-made Jianpi Yishen Formula.The clinical efficacy of the two groups was observed and compared.Results After treatment,the clinical effective rates of the two groups were 88.00%和60.87%,respectively(P<0.05).After treatment,the scores of TCM syndromes in the two groups were significantly reduced compared with those before treatment(P<0.05),and the scores of the observation group were lower than those of the control group(P<0.05).The levels of blood urea nitrogen(BUN)and serum creatinine(SCr)of the two groups were significantly reduced after treatment while the estimated glomerular filtration rate(eGFR)level was significantly elevated(P<0.05),and the level of the observation group was better than that of the control group(P<0.05).Conclusion Self-made Jianpi Yishen Formula has a relatively definite clinical effect in the treatment of CRF,and it can alleviate the clinical symptoms,improve the body′s renal function and accelerate the recovery process of patients.
作者
牛婧
NIU Jing(Department of Endocrinology and Nephrology,Anhui Hospital of Integrated Traditional Chinese and Western Medicine,Hefei 230000,Anhui,China)
出处
《辽宁中医杂志》
CAS
2022年第7期99-101,共3页
Liaoning Journal of Traditional Chinese Medicine
关键词
自拟健脾益肾方
慢性肾衰竭
脾肾亏虚证
临床疗效
Self-made Jianpi Yishen Formula(自拟健脾益肾方)
chronic renal failure
spleen-kidney deficiency syndrome
clinical efficacy
