摘要
目的探究益气养阴、凉血化瘀汤联合西药在糖尿病视网膜病变性(DR)玻璃体积血患者治疗中的应用效果。方法纳入2018年1月—2019年8月80例DR玻璃体积血患者,按住院顺序奇偶数法分为观察组40例(71患眼)、对照组40例(68患眼),对照组予以安妥碘结膜下注射+多贝斯口服,观察组在对照组基础上,联合益气养阴、凉血化瘀汤服用,连续治疗3个月,评价两组眼底变化、视力恢复、血液流变学状态及临床疗效。结果治疗后,两组眼底硬性渗出分级、微血管瘤数目、出血灶面积、黄斑厚度均较治疗前明显减轻(P<0.05),且观察组上述指标改善明显优于对照组(P<0.05);两组视力水平均明显优于治疗前(P<0.05),且观察组优于对照组(P<0.05);两组全血还原黏度、血浆黏度、红细胞压积、纤维蛋白原均较治疗前明显下降(P<0.05),且观察组上述指标均明显低于对照组(P<0.05);观察组总有效率97.18%(69/71),明显高于对照组的85.29%(58/68)(P<0.05)。结论益气养阴、凉血化瘀汤联合西药治疗DR玻璃体积血,可更好减轻患者眼底病变、促进视力恢复、改善血液流变状态,有助于提高临床治疗效果。
Objective To explore the application effects of Yiqi Yangyin,Liangxue Huayu Decoction(益气养阴、凉血化瘀汤)combined with Western medicine in the treatment of diabetic retinopathy(DR)with vitreous hemorrhage.Methods From January 2018 to August 2019,80 patients with DR and vitreous hemorrhage were enrolled and divided into observation group(40 cases,71 affected eyes)and control group(40 cases,68 affected eyes)according to the odd and even number of hospitalization sequence.The control group was given subconjunctival injection of prolonium iodide+calcium dobesilate orally,and the observation group was combined with Yiqi Yangyin,Liangxue Huayu Decoction on the basis of control group,and they were continuously treated for 3 months.The fundus changes,visual acuity recovery,hemorheology status and clinical efficacy were evaluated in the two groups.Results After treatment,the fundus rigid exudation grading,the number of microangiomas,the area of hemorrhagic focus and the thickness of macula in the two groups were significantly reduced compared with those before treatment(P<0.05),and the improvements of the above indicators in the observation group were significantly better than those in the control group(P<0.05).The visual acuity level in the two groups was significantly better than that before treatment(P<0.05),and the level in the observation group was better than that in the control group(P<0.05).The whole blood reduced viscosity,plasma viscosity,hematocrit and fibrinogen in the two groups were significantly decreased compared with those before treatment(P<0.05),and the above indicators in the observation group were significantly lower than those in the control group(P<0.05).The total effective rate in the observation group was significantly higher than that in the control group[97.18%(69/71)vs 85.29%(58/68)](P<0.05).Conclusion Yiqi Yangyin,Liangxue Huayu Decoction combined with Western medicine for DR with vitreous hemorrhage can better reduce the fundus disease,promote the visual acuity recovery,improve the hemorheology status and help to improve the clinical treatment effects.
作者
刘菊芬
黄翠婷
LIU Jufen;HUANG Cuiting(Shangyu People's Hospital in Shaoxing,Shaoxing 312300,Zhejiang,China;Ningde Hospital Affiliated to Fujian Medical University,Ningde 352100,Fujian,China)
出处
《辽宁中医杂志》
CAS
2022年第4期103-106,共4页
Liaoning Journal of Traditional Chinese Medicine
