摘要
目的探究通便汤基础上加用柴胡舒肝散对便秘患者心理障碍的临床疗效。方法收集2018年5月—2018年10月间江苏省中医院肛肠科符合慢性传输型便秘诊断标准的门诊患者共65例(其中男28例,女37例),随机分为治疗组与对照组。所有入组病例均运用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)及90项症状自评量表(SCL-90)评估心理状态。治疗组在通便汤治疗的基础上加用柴胡舒肝散,对照组仅用通便汤进行治疗。治疗1个疗程(8周)后,再次评估两组病例心理状态,分析比较两组之间的心理状态及便秘情况(包括排便间隔、排便困难程度、粪便性状等)。结果两组的便秘情况均较治疗前得到明显改善,两组心理状态在HAMD评分、HAMA评分、SCL-90抑郁、焦虑因子也明显改善(P<0.05),存在统计学意义,且治疗组的降分率高于对照组(P<0.05)。治疗组SCL-90中的躯体化、强迫状态因子较治疗前也存在统计学意义(P<0.05)。结论在通便汤基础上加用柴胡舒肝散对缓解便秘症状有积极的作用,也能改善慢性便秘患者的心理障碍情况。
Objective To explore the clinical effect of using Chaihu Shugan Decoction on the psychological disorders of patients with constipation.Methods A total of 65 outpatients(28 males and 37 females)who underwent the diagnosis of chronic transit constipation in the Anorectal Department of Jiangsu Provincial Hospital of Traditional Chinese Medicine from May 2018 to October 2018 were randomly divided into treatment group and control group.All patients were assessed for mental status using the Hamilton Depression Scale(HAMD),the Hamilton Anxiety Scale(HAMA),and the 90 Symptom Checklist(SCL-90).The treatment group was treated with Chaihu Shugan Decoction on the basis of the treatment of Tongbian Decoction,and the control group was only treated with Tongbian Decoction.After a course of treatment(8 weeks),the psychological status of the two groups was evaluated again,and the psychological status and constipation between the two groups(including the interval of defecation,difficulty in defecation,fecal traits,etc.)were analyzed.Results The constipation of the two groups was significantly improved compared with that before treatment.The psychological status of the two groups was significantly improved in the HAMD score,HAMA score,SCL-90 depression and anxiety factor(P<0.05),and there were statistical differences.The rate of scores reduction in the treatment group was higher than that in the control group(P<0.05).The somatization and compulsive status factors of SCL-90 in the treatment group were also statistically different(P<0.05).Conclusion Chaihu Shugan Decoction on the basis of Tongbian Decoction has a positive effect on relieving constipation symptoms,and also can improve the psychological disorders of patients with chronic constipation.
作者
周肸
钱海华
张丹
曾莉
ZHOU Xi;QIAN Haihua;ZHANG Dan;ZENG Li(The First Clinical Medical College,Nanjing University of Chinese Medicine,Nanjing 210000,Jiangsu,China;Anorectal Department,The Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210000,Jiangsu,China)
出处
《辽宁中医杂志》
CAS
2020年第5期99-102,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81573979)
关键词
慢性便秘
心理障碍
柴胡疏肝散
通便汤
临床观察
chronic constipation
psychological disorder
Chaihu Shugan Decoction
Tongbian Decoction
clinical observation
