摘要
目的探讨多发性硬化(MS)与视神经脊髓炎谱系疾病(NMOSD)临床及脊髓MRI影像特征。方法回顾性分析本院2015年1月至2018年11月间经临床确诊的58例MS及69例NMOSD患者的临床及脊髓MRI资料。结果MS患者出现双上肢麻木较NMOSD患者多,后者出现单侧肢体麻木多于前者(P<0.05);MS病灶易累及颈髓,而NMOSD多累及胸髓,受累节段长,主要位于中央灰质,病灶内易出现亮点征(P<0.05)。结论MS与NMOSD患者临床表现类似,可根据实验室相关检查及脊髓内病灶MRI特征相鉴别,以便早期明确诊断,制定合理的治疗策略。
Objective To investigate the clinical and MRI imaging features of multiple sclerosis(MS)and optic neuritis Spectrum disease(NMOSD).Methods The clinical and spinal MRI data of 58 patients with MS and 69 patients with NMOSD in our hospital from January 2015 to November 2018 were analyzed retrospectively.Results MS patients with double upper limb numbness were more frequent than NMOSD patients and the latter had more numbness of unilateral limbs than the former(P<0.05).MS lesions tend to involve the cervical spinal cord,while the NMOSD lesions typically involves the thoracic cord and the affected segment is long,mainly located in central gray matter and the lesion was also prone to bright spot signs(P<0.05).Conclusion There was a small difference in clinical symptoms between MS and NMOSD,which could be identified according to laboratory-related examinationas and the difference of spinal cord lesions in order to make a clear diagnosis at an early stage and develop a reasonable treatment strategy.
作者
谢艳君
李咏梅
付佳亮
罗琦
王静杰
XIE Yanjun;LI Yongmei;FU Jialiang;LUO Qi(Department of Radiology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,P.R.China)
出处
《临床放射学杂志》
CSCD
北大核心
2020年第5期879-884,共6页
Journal of Clinical Radiology
基金
重庆市卫计委医学科研重点课题(编号:2016ZDXM002)
重庆市卫计委医学科研青年项目(编号:2018QNXM004)
重庆市科学技术委员会-重庆市基础研究与前沿探索专项项目(编号:cstc2018jcyjAX0584)
国家重点研发计划(编号:2016YFC0107109)
