摘要
目的:分析有临床药师参与的1例颅内肺炎链球菌感染患者的临床治疗与药学监护,为该类患者的临床救治和安全合理用药提供参考。方法:临床药师全程参与了该例颅内感染患者的治疗过程,其间依据患者的各项生理指标,结合国内外相关指南、共识和权威资料,协助医生制定个体化的抗感染治疗方案,并开展药学监护,进一步优化调整治疗方案,监测药物不良反应的发生情况。结果:在临床药师和医生的协调配合下,制定出了以万古霉素为核心的治疗方案,而患者的脑脊液病原菌检测结果示肺炎链球菌阳性,验证了治疗方案的准确性;患者治疗后症状很快消失,顺利出院。结论:临床药师在临床应对颅内感染患者时,应尽量准确把握患者的相关症状和指标,尽早开展经验治疗和药学监护,并根据患者病情变化和自身药学特长,及时调整和优化治疗方案已达到治疗效果;同时积极开展治疗药物监测,避免药物不良反应的发生。
Objective:To investigate the clinical treatment and pharmaceutical care of one patient with intracranial Streptococcus pneumoniae infection participated by clinical pharmacist,and to provide reference for the clinical treatment and safe and rational use of drugs in such patients.Methods:The clinical pharmacist participated in the treatment process of the patient with intracranial infection,during which he/she assisted the physician in formulating an individualized anti-infection treatment regimen based on the patient’s physiological indexes and relevant domestic and international guidelines,consensus and authoritative data,and carried out pharmaceutical care to further optimize the treatment regimen and monitor adverse drug reactions.Results:With the coordination and cooperation of the clinical pharmacist and physician,a vancomycin-based treatment regimen was formulated,and the pathogen test results of the patient’s cerebrospinal fluid showed positive Streptococcus pneumoniae,verifying the accuracy of the treatment regimen.The symptoms of the patient disappeared soon after the treatment and the patient was discharged successfully.Conclusion:The clinical pharmacist should try to accurately grasp the relevant symptoms and indexes of patients in clinical response to patients with intracranial infection,carry out empirical treatment and pharmaceutical care as early as possible,and timely adjust and optimize the treatment regimen according to the changes in patients’conditions and their own pharmacy expertise to achieve therapeutic effects.Meanwhile,therapeutic drug monitoring should be carried out actively to avoid adverse drug reactions.
作者
林辉
卢平
冉英
牟银艳
洪鸣
LIN Hui;LU Ping;RAN Ying;MOU Yin-yan;HONG Ming(Lichuan Ethnic Hospital of Traditional Chinese Medicine,Lichuan Hubei 445400,China;Yuanbao Township Health Center,Lichuan Hubei 445424,China;Lichuan Dongcheng Sub-district Office Health Center,Lichuan Hubei 445400,China;Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology,Wuhan Hubei 430030,China)
出处
《抗感染药学》
2022年第6期904-907,共4页
Anti-infection Pharmacy
关键词
颅内感染
肺炎链球菌
药学监护
万古霉素
intracranial infection
Streptococcus pneumoniae
pharmaceutical care
vancomycin
