摘要
外泌体是细胞分泌的一种胞外囊泡,直径为30 ~ 150 nm,作为细胞旁分泌的主要途径,在细胞间通讯中发挥重要作用。外泌体能够促进骨再生并且在骨疾病的发生及发展过程中发挥作用。本文就外泌体在骨再生及骨疾病领域的研究做一综述,为外泌体的研究及临床应用提供参考。
Exosome is a kind of extracellular vesicles secreted by cells with a diameter ranging from 30 to 150 nm.As the main pathway of paracrine secretion,exosome is of great importance in cell-to-cell communication,for it can promote bone regeneration and play a role in the development and progression of bone diseases.This article reviews the research advances in exosomes in the field of bone regeneration and bone diseases,hoping to provide evidences for the research and clinical application.
作者
杨烁
温宁
YANG Shuo;WEN Ning(Department of Stomatology,the First Medical Center,Chinese PLA General Hospital,Beijing 100853,China)
出处
《解放军医学院学报》
CAS
2020年第2期188-191,共4页
Academic Journal of Chinese PLA Medical School
基金
国家自然科学基金面上项目(51972339).
关键词
外泌体
骨再生
骨疾病
exosome
bone regeneration
bone disease
