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重复热处理对大鼠睾丸的支持细胞和间质组织的影响 被引量:3

THE EFFECT OF REPEATED HEATING ON THE SERTOLI CELLS AND THE INTERSTITIAL TISSUE IN THE RAT TESTIS
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摘要 成年大鼠睾丸接受43±0.2℃温水浴25min,每月处理一次。首次加温后1~7天,支持细胞内的溶酶体、脂滴和线粒体数量明显增多。结果指出,热处理不但引起线粒体暂时性增生,同时也加速其变性和解体过程。加温后7~30天,常见支持细胞脱落入管腔,第二次和第三次处理后更为常见。电镜显示,加热对间质细胞的超微结构无损害,但首次加温后2~7天,间质组织内的胶原纤维出现增生。每月加温一次,二次和三次处理后,所有睾丸都呈现纤维化。每65天加温一次,二次处理后,仅见一例睾丸出现轻度纤维化。上述结果表明,睾丸纤维化程度与两次热处理之间的恢复时间长短有关。 The scrotum of mature rats was immersed in a hot water bath(43±0.2℃)for 25 min once each month.One to seven days after the first treatment,the lysosomes,lipid droplets and mitochondria significantly increased in number in the sertoli cells.It also showed that heat treatment accelerated the mitochondria’s degenerative changes and caused the mitochondria temporarily to multiply.The exfoliation of the sertoli cells into tubular lumen were often observed during seven to thirty days after the first heating,the exfoliated sertoli cells became more numerous after the second or the third heating.Examination with electron microscopy showed that heating did not damage the ultrustructure of the interstitial cells,but two to seven days after the first heating,the multiplication of collagen fibress was evident in the interstitial tissue.All the testes showed marked fibrosis after the second or third heating,when the rats were treated once a month,but of the animals were treated once sixty-five days,only an example of the testis showed a slight degree of the fibrosis after the second heating.These results suggest that the degree of the testis fibrosis is related to the duration of the interval between each successive heat treatment.
作者 杨勇正 滕松山 Yang Yongzheng;Teng Songshan(Institute of Biophysics,Academia Sinica,Beijing)
出处 《解剖学报》 CAS 1984年第4期419-423,459-460,共7页 Acta Anatomica Sinica
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