摘要
目的对比子宫肌瘤不同治疗方案[射频消融术、子宫动脉栓塞术(UAE)]的临床效果。方法选取2019年1月—2020年1月期间信阳市人民医院收治的70例子宫肌瘤患者作为研究对象,采用随机数字表法分为2组,各35例。A组采取射频消融术治疗,B组采用子宫动脉栓塞术(UAE)治疗,比较两组围术期指标(手术时间、子宫体积、肌瘤直径、住院时间),比较两组术前及术后3个月的卵巢功能[促卵泡激素(FSH)、雌二醇(E2)、促黄体生成素(LH)],比较两组并发症发生情况(感染、腹痛、恶心呕吐)。结果B组手术时间(104.24±12.64)min、住院时间(4.97±0.59)d长于A组(48.58±6.24)min、(2.83±0.63)d,子宫体积(273.59±17.65)cm^(3)、肌瘤直径(1.21±0.58)cm小于A组(322.58±20.17)cm^(3)、(1.64±0.77)cm,差异有统计学意义(P<0.05);B组FSH(9.25±2.11)mIU/mL、LH(9.08±2.15)mIU/mL水平高于术前(7.71±2.23)mIU/mL、(7.65±2.18)mIU/mL,且B组的FSH(9.25±2.11)mIU/mL、LH(9.08±2.15)mIU/mL水平高于A组(8.21±2.16)mIU/mL、(7.93±2.13)mIU/mL,差异有统计学意义(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05)。结论UAE治疗更利于子宫肌瘤患者子宫体积及瘤体体积的缩小,但射频消融术对子宫肌瘤患者的卵巢功能影响更小,且手术及住院时间更短,两种方案的治疗安全性相当。
Objective To compare the clinical effect of different treatment schemes[radiofrequency ablation,uterine artery embolization(UAE)]for hysteromyoma.Methods Totally 70 patients with hysteromyoma treated in Xinyang People’s Hospital from January 2019 to January 2020 were selected as the research subjects,a random number table method was used to divide them into 2 groups,35 cases in each group.Group A was treated with radiofrequency ablation,group B was treated with uterine artery embolization(UAE),the perioperative indexes(operation time,uterine volume,myoma diameter,hospitalization time)were compared between the two groups,the ovarian function[follicle stimulating hormone(FSH),estradiol(E2),luteinizing hormone(LH)]of the two groups before and 3 months after operation were compared,the occurrence of complications(infection,abdominal pain,nausea and vomiting)was compared between the two groups.Results The operation time(104.24±12.64)min,hospitalization time(4.97±0.59)d in group B were longer than those in group A(48.58±6.24)min,(2.83±0.63)d,uterine volume(273.59±17.65)cm^(3),myoma diameter(1.21±0.58)cm were less than those in group A(322.58±20.17)cm^(3),(1.64±0.77)cm,with statistical significant differences(P<0.05);the levels of FSH(9.25±2.11)mIU/mL and LH(9.08±2.15)mIU/mL in group B were higher than those before operation(7.71±2.23)mIU/mL,(7.65±2.18)mIU/mL,and the levels of FSH(9.25±2.11)mIU/mL and LH(9.08±2.15)mIU/mL in group B were higher than those in group A(8.21±2.16)mIU/mL,(7.93±2.13)mIU/mL,with statistical significant differences(P<0.05);there was no statistical significant difference in the incidence of complications between the two groups(P>0.05).Conclusion UAE treatment is more conducive to the reduction of uterine volume and tumor volume in patients with hysteromyoma,however,radiofrequency ablation has less impact on ovarian function and shorter operation and hospitalization time,the therapeutic safety of the two regimens is similar.
作者
陈静
韩莉莉
CHEN Jing;HAN Li-li(Department of Obstetrics and Gynecology,Xinyang People’s Hospital,Xinyang,Henan 464100,China)
出处
《医药论坛杂志》
2021年第16期41-44,共4页
Journal of Medical Forum
关键词
子宫肌瘤
射频消融术
子宫动脉栓塞术
卵巢功能
Hysteromyoma
Radiofrequency ablation
Uterine artery embolization
Ovarian function
