摘要
△^(5,16,20)-孕甾三烯-3β,20-二醇二乙酸酯(V)经高锰酸钾处理而获得一羟基化产物,此物的结构经初步推定为X,而不是前人所拟的VI.四醇化合物(VIII)用丙酮-高氯酸处理所得的缩丙酮化合物经证明为XII.
1.On treating△^(5,16,20)-pregnatrien-3β,20-diol diacetate(V)with potassium permanganate a hydroxylation product was obtained.Its structure has been assumed to be X instead of VI as proposed previously.2.When the tetrol(VIII)was treated with acetone-perchloric acid,it formed the acetonide XII,but not XIII as reported in the literature.The latter was prepared from another route starting with VI.Based on these results we suspect the correctness of the assumption that 16α,17α,21-trihydroxy-20-keto steroids form 16,17-acetonides under the described conditions.
出处
《化学学报》
SCIE
CAS
1966年第1期58-63,共6页
Acta Chimica Sinica
