摘要
目的:回顾性分析骨化性气管支气管病(TO)与炎症的相关性。方法:收集2013年5月~2019年9月湖南省胸科医院36例TO患者临床资料,应用Spearman相关分析TO与炎症指标的关系。结果:36例TO患者中,入院平均白细胞10.5±3.6*10^9/L、中性比64.8±12.6%、C反应蛋白中位数(四分位数)[M(Q1,Q3)]为6(0.9,45)mg/L、血沉[M(Q1,Q3)]为21.7(7,54.5)mm/h,TO病变累及气道数1-7个,[M(Q1,Q3)]为2.5(2.0,4.8)个,合并肺部感染21例、合并肺结核27例;TO分级与白细胞呈正相关,提示炎症对TO病变严重程度有影响。结论:气道慢性炎症可能是影响TO发展主要因素之一,具体机制还有待进一步研究。
Objective Retrospective analysis of the relationship between tracheobronchopathia osteochondroplastica(TO)and inflammation.Methods The clinical data of 36 patients with TO were collected and analyzed with Spearman correlation analysis.Results Among 36 patients with TO,the average WBC count was 10.5±3.6*10^9/L,the percentage of neutrophils was 64.8+12.6%,and the median(quartile)of CRP was[M(Q1,Q3)]is 6(0.9,45)mg/L,and ESR[M(Q1,Q3)]was 21.7(7,54.5)mm/h.The TO classification was mainly based on I phase(26/36),TO lesions involve 1-7 airway sites[,M(Q1,Q3)]is 2.5(2.0,4.8),21 patients had pulmonary infections,27 had pulmonary tuberculosis;correlation analysis showed that TO classification was positively correlated with leukocytes,suggesting that inflammation has an impact on the severity of TO lesions.Conclusion Inflammation was thought to be a important plausible hypothesis in the course of TO,however,the specific mechanism needs further study.
作者
罗莉
冯妮
肖阳宝
罗林紫
冯丹
Luo Li;Feng Ni;Xiao Yang-bao;Luo Lin-zi;Feng Dan(Hunan Chest Hospital,Changsha 410013,China;The Fourth Hospital of Changsha,Changsha 410006,China)
出处
《湖南师范大学学报（医学版）》
2020年第3期30-32,共3页
Journal of Hunan Normal University(Medical Sciences)
基金
湖南省自然科学基金,科卫联合项目(2019JJ80107)
湖南省自然科学基金青年基金(2019JJ50300)
关键词
骨化性气管支气管病
炎症
肺结核
tracheobronchopathia osteochondroplastica
inflammation
tuberculous
