摘要
目的:探讨冠心病合并2型糖尿病患者的临床特点。方法:连续性前瞻性的招募2015年3月~2018年3月就诊于我院心内科以冠心病为主要诊断且合并2型糖尿病的患者82名归为实验组,同期招募90名明确排除糖尿病的冠心病患者归为对照组,所有患者均施行冠状动脉造影术。随访实验组患者出院后1年内发生主要不良心血管事件(MACE)情况。比较两组患者冠状动脉病变支数的差异;分析实验组患者冠状动脉病变支数的关系入院即刻糖化血红蛋白A1c(HbA1c)的关系以及入院即刻HbA1c与发生主要不良心血管事件(MACE)的关系。结果:与对照组相比,实验组患者双支及三支血管病变的例数显著增多,单支血管病变的例数显著减少;实验组中三支血管病变患者入院即刻HbA1c水平显著高于双支及单支血管病变的患者;实验组中发生MACE的患者入院即刻HbA1c显著高于未发生MACE的患者。结论:合并2型糖尿病的冠心病患者血管病变程度较重,同时血糖控制水平影响冠心病患者预后。
Objective To investigate the clinical characteristics of coronary artery disease(CAD)patients with type 2 diabetes mellitus(T2DM).Methods All of 82 CAD patients with T2DM were collected as Experiment group,and CAD patients without history of diabetes mellitus were collected as Control group at the same time.All of them admitted to cardiology departments and underwent coronary angiography in our hospital between March 2015 and March 2018.The major adverse cardiovascular events(MACE)occurred within 1 year after discharge in Experiment group.To analyze the relationship between the level of hemoglobin A1c at admission and number of coronary artery lesions and major adverse cardiovascular events(MACE)in Experiment group.Results In this study,we found some conclusions like 1)compared with the control group,the number of double-and three-vessel lesions patients in Experiment group were significantly higher,and the number of single-vessel lesions patients were significantly lower;2)the level of HbA1c in patients with three-vessel lesions was significantly higher than others in Experiment group.3)the CAD patients with MACE had a higher HbA1c concentration than those without in Experiment group.Conclusion CAD patients with T2DM had serious vascular lesions,and the prognosis of them were influenced by the level of HbA1c.
作者
梁进
叶平
Liang Jin;Ye Ping(Huainan Oriental Hospital Group General Hospital,Huainan 232001,China)
出处
《湖南师范大学学报（医学版）》
2020年第3期159-162,共4页
Journal of Hunan Normal University(Medical Sciences)
