摘要
目的调查广州市与佛山市(简称广佛地区)0~4岁婴幼儿25-羟基维生素D[25(OH)D]水平,建立广佛地区0~4岁婴幼儿25(OH)D参考区间。方法随机选取2018年1月至2019年8月在佛山市禅城区中心医院和广州市花都区妇幼保健院门诊进行常规健康体检的0~4岁婴幼儿5053名,采用罗氏Cobas e601全自动电化学发光免疫分析仪检测25(OH)D。结果5053名婴幼儿25(OH)D结果呈偏态分布,男、女间差异无统计学意义(P>0.05),广佛地区婴幼儿25(OH)D参考区间为25.90~67.30 ng/mL。随着年龄的增加,广佛地区婴幼儿25(OH)D水平呈现下降趋势(P<0.05);秋季25(OH)D水平高于其它季节(P<0.05)。结论初步建立了广佛地区0~4岁婴幼儿25(OH)D参考区间,不同年龄组25(OH)D参考区间有所不同。
Objective To investigate the level of serum 25-hydroxyvitamin D[25(OH)D]in infants aged 0-4 years in Guangzhou and Foshan,and establish the reference range for serum 25(OH)D in infants aged 0-4 years in Guangzhou and Foshan.Methods 5053 infants aged 0-4 years were randomly selected from those attending Foshan Chancheng Central Hospital and Guangzhou Huadu District Maternal and Child Health Hospital for routine physical examination from January 2018 to August 2019.Serum 25(OH)D was measured using automatic electrochemical luminescence immune analyzer(Roche Consolidated Biological Automated analyzer Systems e601).Results The data distribution of serum 25(OH)D in 5053 infants was skewed.There was no statistically significant difference between males and females(P>0.05).The serum 25(OH)D reference range for infants in Guangzhou and Foshan was 25.90-67.30 ng/mL.With the increase of age,the level of serum 25(OH)D in infants of Guangzhou and Foshan decreased(P<0.05),and it was higher in autumn than that in any other season(P<0.05).Conclusion The reference range for serum 25(OH)D in infants aged 0-4 years in Guangzhou and Foshan was initially established,and it varies with age.
作者
刘伟玲
刘伟旗
刘玉华
胡河
蔡锦河
LIU Weiling;LIU Weiqi;LIU Yuhua;HU He;CAI Jinhe(Department of Clinical Laboratory,Chancheng Centre Hospital,Foshan,Guangdong 528000,China;不详)
出处
《河南预防医学杂志》
2021年第3期225-227,共3页
Henan Journal of Preventive Medicine
