摘要
目的通过分析河南省罗山县40~69岁常住居民胃癌高危人群分布特征,探讨胃癌危险因素对人群的影响,为胃癌防控和早诊早治提供依据。方法采用整群抽样方法,在2个乡镇共调查23657名罗山县常住居民,通过问卷询问获得调查对象的人口学特征、职业危害因素暴露、吸烟、饮酒、饮食、性格、家族史、既往史、临床表现等,根据方案判断胃癌高危人群。先采用χ^(2)检验分析胃癌高危人群影响因素,后将有统计学意义的因素纳入Logistic多因素回归分析。结果共纳入22691名调查对象,检出胃癌高危人群5965人,检出率为26.3%,其中男性检出率为27.6%,女性检出率为24.8%,差异有统计学意义(χ^(2)=22.342,P<0.001);检出率随年龄增加呈下降趋势(χ^(2)_(趋势性)=123.724,P<0.001);多因素结果显示,男性(OR=1.189)、中低年龄组(OR=2.073;OR=1.457)、文盲(OR=1.724)、高收入组(OR=1.802)、中心性肥胖(OR=1.162)、非A型性格(OR=1.348)、饮用浅井水(OR=1.262)或河水(OR=1.542)均为胃癌高危人群的危险因素,中等收入(OR=0.739)是胃癌高危人群的保护因素。结论胃癌高危人群在性别、年龄、文化程度、家庭年收入、中心性肥胖、性格及饮用水来源上存在差异,应采取综合防控策略降低人群危险因素流行水平。
Objective To explore the distribution characteristics and risk factors of high-risk population of gastric cancer among residents aged 40-69 years in Luoshan and provide evidence for prevention and control as well as early detection and treatment of gastric cancer.Methods A total of 23657 permanent residents in two towns of Luoshan were investigated with cluster sampling method.Demographic characteristics,occupational hazard exposure,smoking,drinking,diet,personality,family history,past medical history and clinical symptoms were obtained by questionnaire.Logistic regression analysis was used to analyze the influencing factors after Chi-square tests.Results The detection rate of high-risk factors of gastric cancer in Luoshan was 26.3%among 22691 participants,and the rates were 27.6%in male and 24.8%in female(χ^(2)=22.342,P<0.05);it showed a downward trend with the increase of age(χ^(2)_(trend)=123.724,P<0.001).Results from multivariate logistic regression analysis showed that male(OR=1.189),low or middle-age group(OR=2.073;OR=1.457),illiterate(OR=1.724),high-income group(OR=1.802),central obesity(OR=1.162),non-A personality(OR=1.348),drinking shallow-well water(OR=1.262)or river water(OR=1.542)were risk factors of high-risk population of gastric cancer,and middle-income(OR=0.739)was the protective factor.Conclusion The distribution of high-risk population of gastric cancer in gender,age,education attainment,annual household income,central obesity,personality and drinking water source are different,and comprehensive measures should be taken to reduce prevalence of risk factors.
作者
范雷
戚敏杰
田惠子
朱义功
岳梅军
冯石献
康锴
FAN Lei;QI Minjie;TIAN Huizi;ZHU Yigong;YUE Meijun;FENG Shixian;KANG Kai(Henan Provincial Center for Disease Control and Prevention,Zhengzhou,Henan 450016,China;不详)
出处
《河南预防医学杂志》
2021年第3期166-169,共4页
Henan Journal of Preventive Medicine
基金
河南省卫生厅科技攻关项目(201702275)
关键词
胃癌
高危人群
分布特征
Gastric cancer
High risk population
Distribution characteristics
