摘要
目的探讨青海高原地区不同海拔高度的藏汉世居成年人群中慢性心力衰竭(简称心衰)的患病率与分布特征。方法选取2012年1月至2015年6月青海省西宁、海东2个市和玉树州、海西州、海北州、海南州、黄南州、果洛州6个州共48个县(海拔1800~3000 m、3001~4000 m及4000 m以上3个区间),且在青海省心脑血管病专科医院进行体检的10627例高原健康体检者为研究对象。统计不同民族(藏、汉族)、性别、年龄组人群的心衰患病率,并分析慢性心衰合并高血压、冠心病、肺源性心脏病、高原性心脏病、心脏瓣膜病等疾病的比例。结果调查人群慢性心衰的总体患病率为4.84%,其中男性患病率为5.24%,女性为4.43%,汉族为5.88%,藏族为3.87%,汉族患病率高于藏族(P<0.05);18~44岁、45~59岁、60~74岁、75岁及以上各年龄组的心衰患病率分别为1.76%,3.62%,6.11%,7.88%,随着年龄的增加,心衰患病率逐渐升高;海拔1800~3000 m、3001~4000 m、4000 m以上地区的心衰患病率分别为3.04%,4.36%,7.14%,随着海拔的增加,心衰患病率逐渐升高。慢性心衰患者合并高血压、冠心病、糖尿病、肺心病、心脏瓣膜病的比例均随着年龄、海拔的增加而升高,差异有统计学意义(P<0.05);除肺心病、心脏瓣膜病外,汉族心衰患者合并其他疾病的比例均高于藏族,差异有统计学意义(P<0.05)。结论随着年龄及海拔的增加,青海高原地区人群的心衰患病率呈上升趋势,且藏汉族间患病率有差异。青藏高原青海地区慢性心衰患者合并心血管基础疾病的比例与不同海拔高度、不同年龄阶段及不同民族有关。
Objective To know the prevalence and distribution of chronic heart failure in native adult Tibetan and Han population living in Qinghai plateau area with different elevations.Methods From January 2012 to June 2015,the data of the subjects with plateau health examination in Qinghai Cardiovascular and Cerebrovascular Hospital were collected,from 48 counties in Xining,Haidong,Yushu,Haixi,Haibei,Hainan,Huangnan and Guoluo,and a total of 10672 individuals aged over 18 living at different elevations,namely 1800-3000 m,3000-4000 m and above 4000 m were chosen.Stratified analysis was performed for the prevalence rates of chronic heart failure based on nationality(Tibetan and Han population),gender,age and altitudes.The ratio of heart failure combined with hypertension,coronary heart disease,pulmonary heart disease,hypertensive heart disease and heart valvular disease were analyzed.Results The prevalence of chronic heart failure was 4.84%for whole population,5.24%for male and 4.43%for female,5.88%for Han population,3.87%for Tibetan population respectively,the prevalence of chronic heart failure for Han population was significantly higher than that for Tibetan population,the differences were statistically significant(P<0.05).The prevalences of chronic heart failure in population aged18-44,45-59,60-74 and above 75 were 1.76%,3.62%,6.11%and 7.88%respectively,which increased significantly with age,the differences were statistically significant(P<0.05).The prevalence of heart failure was 3.04%,4.36%and 7.14%for population living at elevations of 1800-3000 m,3000-4000 m and above 4000 m respectively,which increased significantly with the increase of elevations,the differences were statistically significant(P<0.05).The ratio of heart failure combined with hypertension,coronary heart disease,diabetes,pulmonary heart disease,and heart valvular disease increased with the increase of ages and elevations,the differences were statistically significant(P<0.05).The ratio of heart failure combined with other diseases except pulmonary heart disease and heart valvular disease in Han population was higher than that in Tibetan population,the differences were statistically significant(P<0.05).Conclusion The prevalence of heart failure in Qinghai plateau area will increase with the increase of age and altitude,and with significant difference between Tibetan and Han people.The ratio of chronic heart failure combined with cardiovascular underlying medical conditions is associated with elevations,ages and nationalities.
作者
祝存奎
朱芳一
戴婧
邓勇
马生龙
刘楠楠
马元风
厍广东
霍建霞
桑明敏
张生红
马旭莲
ZHU Cun-kui;ZHU Fang-yi;DAI Jing;DENG Yong;MA Sheng-long;LIU Nan-nan;MA Yuan-feng;SHE Guang-dong;HUO Jian-xia;SANG Ming-min;ZHANG Sheng-hong;MA Xu-lian(Department of Internal Medicine,Qinghai Provincial Cardiovascular and Cerebrovascular Hospital,Xining,Qinghai 810012,China)
出处
《环境与健康杂志》
CAS
北大核心
2019年第8期723-726,共4页
Journal of Environment and Health
基金
青海省卫生系统科研重点课题(2017-wjzd-13).
