摘要
目的对辽宁省2006—2015年大气质量与先天性心脏病(简称先心病)进行分析,探讨大气污染与先心病之间的关联,为先心病环境病因学研究提供理论依据。方法采用描述性研究方法,分年度、地区、季度等分析大气质量状况及先心病检出率,并采用生态学研究方法分析大气污染与先心病的关联性。结果辽宁省10年间14个城市API年均值为70.15,其中2006年最高,API年均值以沈阳最高(83.2),丹东最低(61.78),以第一季度最高,第三季度最低,API在不同年度、地区、季度的差异均有统计学意义(P<0.05)。辽宁省10年间先心病检出率为54.52/万,最低为2006年(42.50/万),最高为2008年(66.03/万);14个城市先心病检出率以沈阳最高(84.51/万),铁岭最低(12.83/万);检出率男性高于女性,以第三季度最高(63.98/万),第四季度最低(44.01/万),先心病在不同年度、地区、性别、季度的检出率差异均有统计学意义(P<0.05)。经Spearman等级相关分析,2011—2015年API与先心病检出率呈正相关(rs=0.919,P<0.05)。API值最高的沈阳先心病检出率(84.51/万)高于API值最低的丹东(55.2/万),差异有统计学意义(P<0.05)。处于非采暖期的第二、三季度先心病检出率高于处于采暖期的第一、四季度,差异有统计学意义(P<0.05)。结论辽宁省先心病发生的年度、地区、季度差异可能与大气污染有关。
Objective To analyze the data of congenital heart disease(CHD)and air quality in Liaoning from 2006 to 2015,and to explore the correlation between congenital heart disease and air pollution,and provide theoretical basis for environmental etiology of congenital heart disease.Methods Descriptive study method was used to analyze the detection rate of congenital heart disease and air quality status in different years,regions and seasons.The relationship between congenital heart disease and air pollution was analyzed by ecological research method.Results The average annual API value of 14 cities in Liaoning province in the past 10 years was 70.15,the highest API was found in 2006;The highest API was observed in Shenyang(83.2),the lowest in Dandong(61.78);The highest API was found in the first quarter and the lowest in the third quarter.The differences of API in different years,regions and quarters were statistically significant(P<0.05).In Liaoning province,the detection rate of CHD in 10 years was 54.52/10000,the lowest was in 2006(42.50/10000),the highest was in 2008(66.03/10000);Among 14 cities,the detection rate of CHD was the highest in Shenyang(84.51/10000),the lowest in Tieling(12.83/10000);The detection rate of CHD in male was higher than that in female;The highest detection rate of CHD was in the third quarter(63.98/10000),the lowest in the fourth quarter(44.01/10000);The highest detection rates of CHD in different years,regions,gender and quarters were statistically significant(P<0.05).According to Spearman rank correlation analysis,there was a positive correlation between API and CHD detection rate during 2011-2015(rs=0.919,P<0.05).The detection rate of CHD in Shenyang(84.51/10000)with the highest API value was significantly higher than Dandong(55.2/10000)with the lowest API value(P<0.05).The detection rates of CHD in the non-heating period including the second and the third quarters of season was significantly higher than those in the heating period including the first and the fourth quarters of(P<0.05).Conclusion The interannual,regional and seasonal differences in detection rate of congenital heart diseases might be related to air pollution in Liaoning province.
作者
李静
黄彦红
陈艳玲
姜承志
刘枢
LI Jing;HUANG Yan-hong;CHEN Yan-ling;JIANG Cheng-zhi;LIU Shu(Science and Education Section,Shenyang Maternity and Child Health Hospital,Shenyang,Liaoning 110014,China;不详)
出处
《环境与健康杂志》
CAS
北大核心
2019年第8期709-712,共4页
Journal of Environment and Health
基金
辽宁省科技计划项目(2015225025)
辽宁省科学事业公益研究基金项目(2015001008)
沈阳市科技计划项目(F15-139-9-09).
关键词
先心病
检出率
大气污染
生态学研究
Congenital heart disease
Detection rate
Air pollution
Ecological study
