摘要
目的:观察喘可治注射液雾化在治疗小儿支气管哮喘中的临床疗效。方法:抽选2018年11月—2019年6月我院儿科接收的90例小儿支气管哮喘患儿,据随机数字法分为2组,各45例,对照组予以布地奈德混悬液雾化吸入治疗,研究组在此基础上联合喘可治注射液雾化吸入治疗,观察两组临床疗效,对比患者治疗前后中医症候评分及肺功能指标变化。结果:研究组患儿症状、肺部体征缓解时间明显短于对照组(P<0.05),临床疗效相比对照组明显更高(P<0.05),研究组治疗后肺功能改善情况明显优于对照组(P<0.05),且研究组治疗后中医症候积分水平相比对照组更低(P<0.05)。结论:使用喘可治注射液加强中西医结治疗可有效促进小儿支气管哮喘患儿肺功能改善,缓解症状,提高临床疗效,且药物安全性较高,值得推广。
Objective:To observe the clinical efficacy of Chuankezhi injection,a traditional Chinese medicine(TCM),in the treatment of bronchial asthma in children.Methods:Ninety children with bronchial asthma who were admitted to our hospital from November 2018 to June 2019 were enrolled.According to the random number method,they were divided equally into two groups.The patients in control group were treated with inhalation of aerosolized budesonide suspension,while the patients in Chuankezhi group were treated with inhalation of Chuankezhi injection plus budesonide.The clinical efficacy of the two groups was observed.The TCM symptom scores and lung function indexes before and after treatment were compared.Results:The relief time of symptoms and lung signs in Chuankezhi group was significantly shorter than that in control group(P<0.05),and the clinical efficacy in Chuankezhi group was significantly better than that in control group(P<0.05).The improvement of lung function in Chuankezhi group was significantly better(P<0.05),and the TCM syndrome scores decreased more significantly after Chuankezhi+budesonide treatment(P<0.05).Conclusion:The use of Chuankezhi injection to strengthen the treatment of budesonide inhalation can effectively promote the lung function in children with bronchial asthma,relieve symptoms,and improve clinical efficacy,and no severe adverse effects are found.
作者
谢莹莹
刘洋
XIE Yingying;LIU Yang(Wuhan Asia General Hospital,Wuhan 430056,Hubei,China)
出处
《武汉大学学报（医学版）》
CAS
2020年第6期998-1002,共5页
Medical Journal of Wuhan University
