摘要
目的:回顾性分析潜伏期新型冠状病毒肺炎(COVID-19)患者在手术室环境下的传染性及术后临床转归特征。方法:选取2020年1月份在武汉大学人民医院手术室诊治的处于潜伏期的14例COVID-19患者为研究对象,调查手术室医护人员与患者接触感染情况,分析患者一般情况、临床症状与体征及术后转归情况。结果:手术室有42名医护人员(共47人次)与患者接触而被居家隔离或医学观察,最终有3名医护人员被确诊感染。14例潜伏期患者在术后3~7 d均被确诊感染(SARS-CoV-2核酸阳性);在症状体征方面,12例术后出现发热、10例感到疲劳乏力、9例出现干咳;在术后转归方面,1例患者死亡,13例(包括1例轻型、7例普通型、5例重型)患者转至定点单位继续隔离观察治疗。结论:潜伏期COVID-19患者在手术室环境下亦具有较高的传染性,应提高疫情期间医护人员的防护级别;麻醉手术应激会加重新冠肺炎患者病情,恶化患者术后转归,疫情爆发期间不宜进行择期手术。
Objective:To analyze the infectivity of latent coronavirus disease 2019(COVID-19)in the oper-ating room,and describe their postoperative outcomes.Methods:Fourteen surgical patients with la-tent SAR-CoV-2 infection in January 2020,in Renmin Hospital of Wuhan University were selected as the research objects.We investigated the contact infection between medical staff and patients.The general information,clinical symptoms and signs,and postoperative outcome of the patients were also analyzed.Results:In the operating room,42 healthcare workers(47 person-times in total)were iso-lated under medical observation after contacting with the patients.At last,3 healthcare workers were diagnosed as COVID-19.All these 14 patients were laboratory-confirmed SARS-CoV-2 infection in 3-7 days after surgery.In terms of signs and symptoms,12 patients had fever,10 patients felt fa-tigue,and 9 patients had dry cough.In terms of postoperative outcome,1 patient died,13 patients(including 1 mild,7 general,and 5 severe cases)were transferred to the designated hospitals according to the local health committee.Conclusion:Patients with SARS-CoV-2 infection are highly infectious even in the operating room environment.The stress of anesthesia and operation may exacerbate the progression of COVID-19,and worsen the outcome of patients.
作者
苏娃婷
雷少青
贾一帆
夏正远
夏中元
SU Wating;LEI Shaoqing;JIA Yifan;XIA Zhengyuan;XIA Zhongyuan(Dept.of Anaesthesiology,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei,China)
出处
《武汉大学学报（医学版）》
CAS
2020年第5期702-705,共4页
Medical Journal of Wuhan University
基金
国家自然科学基金资助项目(编号:81700733)
关键词
新型冠状病毒肺炎
临床特征
潜伏期
传染性
术后转归
Coronavirus Disease 2019
Clinical Characteristics
Latent Period
Infectivity
Postoperative Outcome
