摘要
当前新型冠状病毒肺炎(COVID-19)的暴发流行对人民健康造成了很大影响。糖皮质激素曾用于病毒性肺炎的治疗,其主要机理是抑制炎症反应,但糖皮质激素在COVID-19患者中的治疗效果尚不明确。此外,糖皮质激素在治疗其他的病毒性肺炎过程中出现过较多的不良反应。临床专家对糖皮质激素在COVID-19的治疗过程中的作用仍有较大的争议。本文对现阶段糖皮质激素治疗COVID-19的机制、时机、剂量、疗程及优缺点进行了综述。
The breakout of coronavirus disease 2019(COVID-19)has great impact on human health.The main mechanism of glucocorticoids in the treatment of viral pneumonia is to suppress inflammatory responses.However,the therapeutic effect of glucocorticoids in COVID-19 patients is not clear.In addition,glucocorticoids had certain adverse effect in the treatment of other viral pneumonia.There is still much controversy among clinical experts about the use of glucocorticoids in COVID-19.This article reviews the mechanism,time,dose,treatment,advantages and disadvantages of glucocorticoids in the treatment of COVID-19.
作者
陈倩
裴茂华
王瑶
龚作炯
CHEN Qian;PEI Maohua;WANG Yao;GONG Zuojiong(Dept.of Infectious Disease,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei,China)
出处
《武汉大学学报（医学版）》
CAS
2020年第4期560-564,共5页
Medical Journal of Wuhan University
