摘要
文章为评估北方某稀土矿区地下水污染对生物的毒理损伤程度,首先调查了矿区2个地下水样点中重金属含量,其次系统性研究了受污染地下水对小鼠在"个体-器官-组织-细胞"水平的生物损伤程度及其相关性。综合结果表明:白云鄂博矿区地下水中主要污染重金属为Mn、Pb和Cr,尤其Mn含量超标严重,其中重金属在肝脏中积累量为Zn>Cr>Cu>Mn>Ni>Pb>Cd>Co,在肾脏中积累量为Cr>Zn>Mn>Cu>Ni>Pb>Co>Cd,且肝脏中蓄积的重金属Cu、Zn、Cd与肝体比呈显著负相关(r>0.8);肾脏中蓄积的重金属Mn、Cr、Co、Pb、Cd与肾体比呈显著负相关(r>0.8)。组织病理学和细胞形态学检测发现,矿区地下水对小鼠的肝、肾在组织和细胞水平均有不同程度的损伤效应,且荧光定量分析结果进一步验证了损伤效应。结果表明该稀土矿区地下水中重金属会对小鼠肝、肾产生不同程度的生物损伤。
This study was intended to evaluate the biological damage degree from polluted groundwater in a rare earth mining area in North,Baotou City,Inner Mongolia.Firstly,the heavy metal component from two sites in the mining area were investigated,and then the correlation between contaminated groundwater the biological damage degree to mice at the level of"individual-organ-tissue-cell"were systematically studied.The results showed that the main pollution of heavy metals in the mine groundwater was Mn,Pb,Cr.In particular,the content of Mn exceeded more seriously.Moreover,the accumulation of heavy metals in the liver was ranked as Zn>Cr>Cu>Mn>Ni>Pb>Cd>Co,while that in the kidney was Cr>Zn>Mn>Cu>Ni>Pb>Co>Cd.Histopathological and cell morphological results showed that the liver and kidney of mice had a degree of damage at the tissue and cell levels,and it was further verified by qRT-PCR.In conclusion,heavy metals in the groundwater of a rare earth mining area in North could cause biological damage to the liver and kidney of mice.
作者
袁婷
张海红
姜欣颖
杨慧
佟瑞莹
贺小英
郑春丽
YUAN Ting;ZHANG Haihong;JIANG Xinying;YANG Hui;TONG Ruiying;HE Xiaoying;ZHENG Chunli(School of Energy and Environment,Baotou 014010,China;School of Life Science and Technology,Inner Mongolia University of Science&Technology,Baotou 014010,China)
出处
《环境科学与技术》
CAS
CSCD
北大核心
2020年第3期170-176,共7页
Environmental Science & Technology
基金
内蒙古自治区科技计划项目
国家重点研发计划项目(2018YFC1802904)
国家自然科学基金地区项目(31960267,NSFC41561094)
内蒙古科技成果转化专项项目
关键词
稀土矿区
重金属
小鼠
生物损伤
rare earth mining area
heavy metals
mice
biological damage
