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全身麻醉和椎管内麻醉对骨科手术患者术后精神状态、认知功能的影响 被引量:25

Effect of general anesthesia and spinal anesthesia on the postoperative mental state and cognitive function of patients undergoing orthopedic surgery(old age)
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摘要 目的分析全身麻醉、椎管内麻醉应用于骨科手术患者(高龄)对其术后精神状态、认知功能的影响。方法选取2016年3月~2019年3月我院收治的骨科手术高龄患者200例,将其随机分为2组,各100例。将全身麻醉应用于对照组,将椎管内麻醉应用于观察组。比较两组麻醉药物用量、语言陈述时间、术后精神状态(MMSE评分)、认知功能程度以及不良事件发生情况。结果在麻醉药物用量、语言陈述时间上,观察组均少于对照组(P<0.05)。在MMSE评分上,两组术后1.5h、5.5h、11.5h、24 h对比存在统计学差异(P<0.05)。在认知功能上,术后苏醒时对照组正常率53.0%,低于观察组的89.0%(P<0.05)。在精神错乱、认知障碍上,观察组分别为10.0%、6.0%,低于对照组的40.0%、26.0%(P<0.05)。结论椎管内麻醉应用于骨科手术患者(高龄)的效果优于全身麻醉,前者可有效促进患者术后早期精神状态恢复,可改善其认知功能,减少麻醉药物用量和语言陈述时间,还能减少不良事件。 Objective To analyze the effects of general anesthesia and spinal anesthesia on the postoperative mental state and cognitive function of patients undergoing orthopedic surgery(old age).Methods From March 2016 to March 2019,200 elderly patients with orthopedic surgery admitted to our hospital were randomly divided into two groups,100 cases in each.General anesthesia was applied to the control group,and spinal anesthesia was applied to the observation group.The doses of anesthetic drugs,language presentation time,postoperative mental status(MMSE score),cognitive function,and adverse events were compared between the two groups.Results In the dose of anesthetic drugs and language presentation time,the observation group was less than the control group(P<0.05).On the MMSE score,there was a statistical difference between the two groups at 1.5 h,5.5 h,11.5 h,and 24.h(P<0.05).In terms of cognitive function,the normal rate of the control group was 53.0%,which was lower than that(89.0%)in observation group(P<0.05).In the insanity and cognitive impairment,the incidence of the control group was 40.0%and 26.0%,respectively,which were higher than those(10.0%and 6.0%)in the observation group(P<0.05).Conclusion The effect of spinal anesthesia on patients with orthopedic surgery(older age)is better than general anesthesia.The former can effectively promote the recovery of early postoperative mental state,improve their cognitive function,reduce the amount of anesthetic drugs and the time of language presentation.
作者 李新帅 孟帆 LI Xinshuai;MENG Fan(Department of Anesthesiology,Nanyang Central Hospital,Nanyang 473000,China)
出处 《国际精神病学杂志》 2020年第1期107-109,共3页 Journal Of International Psychiatry
关键词 全身麻醉 椎管内麻醉 骨科手术 认知功能 General anesthesia Spinal anesthesia Orthopedic surgery Cognitive function
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