摘要
目的:探讨外耳道冲洗联合曲安奈德益康唑乳膏涂抹治疗真菌性外耳道炎的效果。方法:105例真菌性外耳道炎患者,随机法进行分组。所有患者实施内镜下外耳道冲洗,然后对照组(n=52)给予酒精灌耳,观察组(n=53)给予曲安奈德益康唑乳膏涂抹。观察两组治疗效果、真菌转阴、不良反应及半年内随访的复发情况。结果:观察组治疗效果优于对照组(P<0.05);治疗后半年内,观察组复发率1.8%,低于对照组11.5%(P<0.05);观察组真菌转阴率84.9%,高于对照组67.3%(P<0.05);治疗期间,观察组不良反应发生率低于对照组(P<0.05)。结论:外耳道冲洗联合曲安奈德益康唑乳膏涂抹治疗真菌性外耳道炎有助真菌转阴,减少不良反应,提高治疗效果。
Objective:To investigate the effects of external auditory canal irrigation combined with triamcinolone acetonide and econazole cream in the treatment of fungal otitis externa.Methods:105 cases of fungal otitis externa in our hospital were randomly divided into two groups.All the patients received external auditory canal irrigation under endoscope.52 patients in the control group were given alcohol irrigation,while another 53 patients in the observation group were given triamcinolone acetonide and econazole cream.Then,the treatment effect,fungal colony,incidence of adverse reactions,and recurrence rate within half a year’s follow-up were compared.Results:The therapeutic effect of observation group was better than control group(P<0.05).Within half a year after treatment,the recurrence rate of observation group was 1.8%,which was lower than 11.5%of control group(P<0.05).The fungal negative conversion rate in observation group was 84.9%,which was higher than 67.3%in control group(P<0.05).During treatment,the incidence of adverse reactions in observation group was lower than that in control group(P<0.05).Conclusion:External auditory canal irrigation combined with triamcinolone acetonide and conazole cream treatment for fungal otitis externa can help the fungus to turn negative,reduce adverse reactions and improve the therapeutic effect.
作者
张卫杰
李利红
李瑛
毕瑞鹏
ZHANG Weijie;LI Lihong;LI Ying(Dept.of Otolaryngology Head and Neck Surgery,the 3rd People’s Hospital of Henan Province,Zhengzhou 450000,China)
出处
《华夏医学》
CAS
2021年第1期134-137,共4页
Acta Medicinae Sinica
关键词
外耳道冲洗
真菌性外耳道炎
曲安奈德益康唑乳膏
真菌转阴
external auditory canal irrigation
fungal otitis externa
triamcinolone acetonide and econazole cream
fungal negative conversion
