摘要
目的:探讨右美托咪定分别配合七氟烷、丙泊酚在老年腹腔镜手术麻醉中的效果观察。方法:选取50例老年腹腔镜手术患者,随机分为观察组与对照组,每组各25例。观察组患者采用右美托咪定配合七氟烷维持麻醉;对照组患者采用右美托咪定配合丙泊酚维持麻醉。结果:观察组患者术后3 h,6 h的MMSE评分明显高于对照组(P<0.05);拔管、睁眼、自主呼吸恢复时间皆短于对照组(P<0.05);插管后(T1)、拔管后(T2)的心率(HR)与平均动脉压(MAP)均高于对照组(P<0.05)。结论:右美托咪定配合七氟烷相比于配合丙泊酚,在老年腹腔镜手术麻醉中治疗效果更佳,能够显著缩短拔管、睁眼、自主呼吸恢复时间,对血流动力学和术后认知功能的影响更小。
Objective: To investigate the effects of dexmedetomidine respectively combined with sevoflurane and propofol in elderly patients under laparoscopic anesthesia. Methods: 50 elderly patients undergoing laparoscopic surgery were randomized into the observation group(n=25)and control group(n=25). Dexmedetomidine combined with sevoflurane was used to maintain anesthesia in the observation group and dexmedetomidine combined with propofol was used to maintain anesthesia in the control group. Results: The MMSE scores of 3 h and 6 h after operation in the observation group were significantly higher than those in the control group(P<0.05), and the time of extubation and open eyes, and the recovery time of spontaneous respiration were shorter than that of the control group(P< 0.05), and heart rate(HR)and mean arterial pressure(MAP)after intubation(T1)and after extubation(T2)were all higher than those of the control group(P<0 5). Conclusion: Compared with dexmedetomidine combined with propofol, dexmedetomidine combined with sevoflurane has better therapeutic effect in anesthesia of laparoscopic surgery in elderly patients, and it can significantly shorten the time of extubation, open eyes and spontaneous respiratory recovery. It has less effect on hemodynamics and postoperative cognitive function.
作者
黄丹辉
王远胜
黄俊伟
邓金瑞
HUANG Danhui;WANG Yuansheng;HUANG Junwei(Dept.of Anesthesiology,Jiangmen Central Hospital,Jiangmen 529000,China)
出处
《华夏医学》
CAS
2020年第2期55-57,共3页
Acta Medicinae Sinica
关键词
右美托咪定
七氟烷
丙泊酚
腹腔镜
dexmedetomidine
sevoflurane
propofol
laparoscope
