摘要
随着我国晚婚晚育及多胎多产比例的升高,围生期心肌病(PPCM)的发病率近年明显上升,已成为中国孕产妇除产科因素外的主要死亡原因。但我国临床医生对PPCM的认识和重视程度普遍不够,漏诊率和误诊率也高,导致我国PPCM致死率和致残率居高不下。因此,依据国内外最新研究进展,并结合我国的国情和临床实践,中国医师协会心力衰竭专业委员会组织专家编写了《围生期心肌病诊断和治疗中国专家共识2021》,主要介绍了PPCM的定义和流行病学,病因和病理生理机制,临床表现和辅助检查,诊断与鉴别诊断,PPCM患者急性心力衰竭、稳定性和慢性心力衰竭的处理,以及器械治疗和心脏移植等其他处理,期望为临床医生处理PPCM患者提供指导意见。
With the increasing trend of late marriage and late childbirth as well as multiple children in China, the incidence of peripartum cardiomyopathy (PPCM) has increased significantly in recent years and become the leading cause of death outside obstetric factors for pregnant women in China. The awareness and attention of Chinese clinicians to PPCM, however, are broadly inadequate, causing widespread under-diagnosis and misdiagnosis, which are responsible for the persistently high mortality and morbidity rates of PPCM in China. Based on the latest research findings both at home and abroad, and fully accounting for the national conditions and domestic clinical practices, the Chinese Heart Failure Association of Chinese Medical Doctor Association dedicated an expert group to develop the Chinese Expert Consensus on the Diagnosis and Treatment of Peripartum Cardiomyopathy 2021. To provide guidance in the management of patients with PPCM for clinicians, the consensus report introduces definition and epidemiology of PPCM, its etiology and pathophysiologic mechanisms, clinical manifestations and auxiliary examinations, diagnosis and differential diagnosis, and the management of acute heart failure, stable and chronic heart failure, mechanical therapy and heart transplantation in PPCM patients.
关键词
心肌病
围生期
心力衰竭
妊娠
Cardiomyopathy,peripartum
Heart failure
Pregnancy