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基于RCT的轻度阿尔茨海默病患者阅读治疗效果评价

Application Effect of Bibliotherapy on Patients with Mild Alzheimer's Disease Based on RCT
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摘要 目的评价阅读治疗对轻度阿尔茨海默病(AD)患者的临床效果。方法选取2020年12月-2021年12月期间在我院诊治的80例轻度阿尔茨海默病患者为研究对象,采用随机数字表法分为对照组和治疗组,各组40例。对照组采用常规治疗,治疗组在对照组基础上联合应用阅读治疗,观察比较两组不同治疗时间段(0、3、6、9、12月)简明精神病量表(BPRS)、简明智力状态检查(MMSE)以及日常生活能力量表(ADL)评分。结果治疗3个月、6个月、9个月、12个月后,2组患者BPRS评分均低于治疗前,MMSE、ADL评分均高于治疗前,且治疗组BPRS评分均低于对照组,MMSE、ADL均高于对照组,差异有统计学意义(<0.05)。结论阅读治疗轻度阿尔茨海默病效果确切,可提高患者日常生活能力、认知水平,减轻简明精神病临床症状,是一种可行、有效的治疗方法,值得临床加以应用。 Objective To evaluate the clinical efficacy of reading therapy in patients with mild Alzheimer's disease(AD).Methods Eighty patients with mild Alzheimer's disease,who were treated in our hospital from December 2020 to December 2010,were randomly 2021 into control group and treatment group,with 40 cases in each group.The control group was treated with conventional therapy,and the treatment group was treated with reading therapy in addition to the control group,the scores of brief psychiatric rating scale-BPRS-RRB-PRS),mini-mental state examiMMSEon(MMSE)and activity of daily ADLing(ADL)were compared between the two groups at different time points(0,3,6,9,12 months).Results After 3 months,6 months,9 months and 12 months of treatment,the scores of BPRS were lower,the scores of MMSE and ADL were higher in both groups than before treatment,and the scores of BPRS in the treatment group were lower than those in the control group,mMSE and ADL were significantly higher than those in the control group(P<0.05).Conclusion The effect of reading therapy on mild Alzheimer's disease is definite,it can improve the patients'ability of daily living and cognitive level,and reduce the clinical symptoms of brief psychosis.It is a feasible and effective treatment method,it is worthy of clinical application.
作者 陈小清 关锟联 唐柳岚 CHEN Xiao-qing;GUAN Kun-lian;TANG Liu-lan(Suixi People's Hospital,Zhanjiang 524300,Guangdong,China;Guangzhou Civil Affairs Bureau Psychiatric Hospital,Guangzhou 510430,Guangdong,China)
出处 《医学信息》 2022年第S01期67-69,共3页 Journal of Medical Information
关键词 阿尔茨海默病 阅读治疗 认知功能 Alzheimer's disease reading therapy cognitive function
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