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紫杉醇联合奈达铂治疗晚期食管癌疗效观察

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摘要 目的观察紫杉醇联合奈达铂治疗晚期食管癌的近期临床疗效和不良反应.方法39例晚期食管鳞癌患者给予紫杉醇与奈达伯联合治疗,紫杉醇135~175 mg/m^(2),第1天;奈达铂30mg/m^(2),第2~4天,21d为1个周期,至少进行2个周期后评价.结果39例患者中完全缓解3例,部分缓解20例,稳定10例,进展6例.不良反应主要为剂量限制性毒性,表现为Ⅲ~Ⅳ度骨髓抑制.结论紫杉醇联合奈达铂治疗晚期食管癌疗效较好,不良反应可以耐受.
作者 唐富龙
机构地区 河北省涿鹿县医院肿瘤科
出处 《中国医师进修杂志》 2011年第S01期86-87,共2页 Chinese Journal of Postgraduates of Medicine
关键词 药物疗法 联合 食管肿瘤
分类号 R4 [医药卫生—临床医学]
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中国医师进修杂志
2011年 第S01期

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