摘要
百日咳是一种具有高度传染性的急性呼吸道疾病,婴幼儿(尤其小婴儿)患百日咳后易出现重症,住院率及病死率高.目前重症百日咳的发病机制尚未阐明,临床实践中缺乏规范统一的重症百日咳诊断标准.现综述文献报道重症百日咳时使用的诊断名称和依据,并总结百日咳死亡的危险因素,为重症百日咳临床实践和研究提供参考,促进重症百日咳诊断和治疗的早日规范.
Pertussis is an acute highly contagious respiratory disease,which is associated with high rate of hospitalization and death in infants and young children.The pathogenesis of severe pertussis has not been elucidated,and there has not been a consistent universal definition in severe pertussis.This article summarizes the present clinical definitions of severe pertussis related diagnosis,and the risk factors for death from pertussis.This text could benefit the clinical practice and the further researches,and to contribute to establish a regulation of the diagnosis and treatment of severe pertussis early.
作者
姚开虎
李丽君
Yao Kaihu;Li Lijun(Key Laboratory of Major Diseases in Children,National Key Discipline of Pediatrics(Capital Medical University),National Clinical Research Center for Respiratory Diseases,Beijing Key Laboratory of Pediatric Respiratory Infection Diseases,Beijing Pediatric Research Institute,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Department of Respiration,Guangzhou Women and Children′s Medical Center,Guangzhou 510623,China)
出处
《中华实用儿科临床杂志》
CSCD
北大核心
2019年第22期1681-1685,共5页
Chinese Journal of Applied Clinical Pediatrics
基金
国家自然科学基金(81973100).
关键词
重症百日咳
高白细胞血症
肺动脉高压
换血治疗
体外膜肺氧合
Critical/severe pertussis
Hyperleukocytosis
Pulmonary hypertension
Exchange transfusion
Extracorporeal membrane oxygenation
