摘要
Objective:To evaluate the cytotoxicity of Phaleria macrocarpa fruits extracts.Methods:The cytotoxicity test was carried out by in vitro MCF-7 cell line and in vivo brine shrimp lethality bioassay.Results:The preliminary phytochemical test showed the presence of alkaloids,carbohydrate,glycosides,saponin,terpene,steroids,phenols and flavonoids.The MTT-assay results showed that the highest percentage of cell viability was 106.23%at concentration of 1.25μL and the lowest percentage was 13.04%at concentration of 10μL.Conclusions:The MTT-assay and brine shrimp lethality bioassay results showed that the extract was non-toxic and it would be consumable as a herbal remedy.
