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温和灸、隔盐灸联合穴位贴敷防治乳腺癌化疗后恶心呕吐效果及对血清胃蛋白酶原的影响

Effect of Mild Moxibustion,Salt Separated Moxibustion and Acupoint Application on Nausea and Vomiting after Chemotherapy of Breast Cancer and Its Influence on Serum Pepsinogen
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摘要 目的分析温和灸、隔盐灸联合穴位贴敷对乳腺癌化疗患者的影响.方法选取2023年1月—2023年9月威海市妇幼保健院收治的500例乳腺癌化疗患者为研究对象,按随机数字表法将其分为对照组和观察组,各250例.对照组行托烷司琼联合穴位贴敷治疗,观察组在对照且基础上加以温和灸、隔盐灸治疗.对比两组恶心呕吐发生率、恶心呕吐程度、血清胃蛋白酶原水平及生活质量.结果观察组恶心呕吐发生率为10.40%,低于对照组的17.60%,差异有统计学意义(P<0.05).观察组恶心呕吐程度轻于对照组,差异有统计学意义(P<0.05).化疗后,观察组胃蛋白酶原Ⅰ水平为(83.41±10.53)μg/L,胃蛋白酶原Ⅱ水平为(13.49±1.35)μg/L,均低于对照组的(101.35±11.77)μg/L、(15.21±1.89)μg/L,组间差异有统计学意义(P<0.05).化疗后,观察组生活质量综合评定问卷各个维度评分分别为(79.96±4.88)分、(78.53±4.29)分、(80.24±5.34)分、(79.95±4.53)分,均高于对照组的(70.53±4.21)分、(69.64±3.45)分、(71.63±4.57)分、(70.88±3.61)分,组间差异有统计学意义(P<0.05).结论温和灸、隔盐灸联合穴位贴敷可有效的降低乳腺癌化疗患者恶心呕吐发生率,调节胃蛋白酶原水平,有助于生活质量的提高,有一定的应用价值. Objective To analyze the influence of mild moxibustion,salt separated moxibustion and acupoint application on breast cancer patients undergoing chemotherapy.Methods 500 patients with breast cancer undergoing chemotherapy in Weihai Maternal and Child Health Hospital from January 2023 to September 2023 were selected as the research objects and divided into a control group and an observation group according to random number table,with 250 cases in each group.The control group received treatment with tropisetron and acupoint application,while the observation group received mild moxibustion and salt separated moxibustion on the basis of the control group.The incidence,severity,serum pepsinogen levels of nausea and vomiting and quality of life between two groups were compared.Results The incidence of nausea and vomiting in the observation group was 10.40%,which was lower than the control group's 17.60%,and the difference was statistically significant(P<0.05).The degree of nausea and vomiting in the observation group was milder than that in the control group,and the difference was statistically significant(P<0.05).After chemotherapy,the level of pepsinogenⅠin the observation group was(83.41±10.53)μg/L,the level of pepsinogenⅡwas(13.49±1.35)μg/L,which were lower than(101.35±11.77)μg/L,(15.21±1.89)μg/L in the control group,there were statistically significant differences between groups(P<0.05).After chemotherapy,the Comprehensive Evaluation Questionnaire for Quality of Life scores in the observation group were(79.96±4.88)points,(78.53±4.29)points,(80.24±5.34)points,and(79.95±4.53)points in all dimensions,which were higher than(70.53±4.21)points,(69.64±3.45)points,(71.63±4.57)points,and(70.88±3.61)points in the control group,respectively,and the differences between the groups were statistically significant(P<0.05).Conclusion Mild moxibustion,salt separated moxibustion and acupoint application can effectively reduce the incidence of nausea and vomiting in patients with breast cancer undergoing chemotherapy,regulate the level of pepsinogen,help improve the quality of life,have certain application value.
作者 洪炜 孟祥悦 HONG Wei;MENG Xiangyue(Department of Breast Health,Weihai Maternal and Child Health Hospital,Weihai Shandong,264200,China)
出处 《反射疗法与康复医学》 2024年第4期4-7,共4页 Reflexology And Rehabilitation Medicine
关键词 乳腺癌 化疗 温和灸 隔盐灸 穴位贴敷 恶心呕吐 Breast cancer Chemotherapy Mild moxibustion Salt separated moxibustion Acupoint application Nausea and vomiting
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