摘要
目的探讨《普济方》中医鼻疗法治疗头痛的用药特色。方法收集《普济方》中鼻疗治疗头痛的方剂,结合频数分析、关联规则、聚类分析、因子分析等数据挖掘方法,分析头痛鼻疗方中药物的使用频次、关联药对、核心组合与方剂及常用配伍选择。结果共筛选出头痛鼻疗方101首,涉及药物98种,使用频次≥5的药物有22味,使用频次排在前3的药物分别是川芎、细辛和芒硝。得到关联药对22组,置信度较高的有石膏-川芎、薄荷-川芎、樟脑-青黛等。聚类分析得到两个核心方剂组合,第一个组成有青黛、樟脑、薄荷;第二个组成有生姜、甘草、荜茇、高良姜、茶叶、川乌、冰片。通过因子分析得到常用的配伍药物选择包括樟脑、石膏、细辛、白芷等。结论《普济方》以鼻疗法治疗头痛时具有以通为用、以泄代补、芳香走窜、量少力专等用药特点,且选药注重“简、便、廉、验”,多适用于风寒、风热、瘀血等实证头痛。
Objective To explore the characteristics of nasal treatment of headache with traditional Chinese medicine in Prescriptions for Universal Relief.Methods The prescriptions for treating headache by nose in Prescriptions for Universal Relief were collected,combined with data mining methods such as frequency analysis,association rules,cluster analysis,factor analysis and so on.The frequency of drug use,related drug pairs,core combinations and prescriptions and common compatibility choices in headache and nasal treatment prescriptions were analyzed.Results 101 headache and nasal prescriptions were selected,involving 98 kinds of drugs,22 drugs with frequency≥5,and the top 3 most frequently used drugs were ligusticum chuanxiong,asarum and mirabilite.22 groups of related drugs were obtained,and the ones with high confidence were gypsum-Ligusticum chuanxiong,peppermint-Ligusticum chuanxiong,camphor-Qing Dai and so on.Two core prescription combinations were obtained by cluster analysis,the first was Qing Dai,camphor and peppermint,and the second was ginger,licorice,Piper longum,Gaoliang ginger,tea,Chuanwu and borneol.Through factor analysis,it is found that the commonly used compatible drugs include camphor,gypsum,Asarum,Angelica dahurica and so on.Conclusion Prescriptions for Universal Relief has the characteristics of"Tong","catharsis instead of tonic",aromatic,low dose and special use in the treatment of headache,and the drug selection pays attention to"simplicity,convenience,cheapness and efficiency".It is more suitable for empirical headache such as wind-cold,wind-heat,blood stasis and so on.
作者
王家妤
许佳烨
周豪坤
吴佳豪
钱俊华
WANG Jiayu;XU Jiaye;ZHOU Haokun;WU Jiahao;QIAN Junhua(First Clinical Medical College,Zhejiang Chinese Medical University,Hangzhou Zhejiang,310053,China;Department of Internal Medicine,Hangzhou Traditional Chinese Medicine Hospital,Hangzhou Zhejiang,310007,China;Basic Medicine College,Zhejiang Chinese Medical University,Hangzhou Zhejiang,310053,China)
出处
《反射疗法与康复医学》
2023年第18期7-11,15,共6页
Reflexology And Rehabilitation Medicine
关键词
普济方
数据挖掘
中医鼻疗法
外治法
头痛
用药特色
Prescriptions for Universal Relief
Data mining
Nasal therapy
External treatment
Headache
Administration features
