摘要
目的探究沙丁胺醇联合布地奈德对支气管哮喘患儿症状消失时间及肺功能的影响.方法选取2020年5月—2022年5月本院收治的72例支气管哮喘患儿为研究对象,采用抽样检测法分为对照组及观察组,每组36例.在常规治疗基础上,对照组采用布地奈德治疗,观察组采用布地奈德联合沙丁胺醇治疗,均持续7d.比较两组患儿的临床疗效、症状消失时间、肺功能指标及不良反应.结果观察组的治疗总好转率为91.67%,高于对照组的72.22%,差异有统计学意义(P<0.05).治疗后,观察组的肺内哮鸣音、咳嗽、胸闷气短消失时间分别为(5.04±0.46)d、(4.27±0.30)d、(2.87±0.25)d,均短于对照组的(7.62±0.63)d、(7.26±0.35)d、(5.35±0.43)d,组间差异有统计学意义(P<0.05).治疗后,观察组的各项肺功能指标水平均优于对照组,组间差异有统计学意义(P<0.05).两组的不良反应发生率比较,差异无统计学意义(P>0.05).结论采用沙丁胺醇联合布地奈德治疗支气管哮喘患儿的疗效确切,可加速症状消退,改善其肺功能.
Objective To investigate the effect of salbutamol combined with budesonide on symptom disappearance time and pulmonary function in children with bronchial asthma.Methods A total of 72 children with bronchial asthma admitted to our hospital from May 2020 to May 2022 were selected as the research objects and were divided into a control group and an observation group by sampling detection,with 36 cases in each group.On the basis of conventional treatment,the control group was treated with budesonide,and the observation group was treated with budesonide combined with salbutamol.Both groups lasted for 7 days.The clinical efficacy,symptom disappearance time,pulmonary function indexes and adverse reactions were compared between the two groups.Results The total improvement rate of the observation group was 91.67%,which was higher than 72.22%of the control group,and the difference was statistically significant(P<0.05).After treatment,the disappearance time of wheezing,coughing and chest tightness in the observation group were(5.04±0.46)d,(4.27±0.30)d and(2.87±0.25)d,respectively,which were all shorter than(7.62±0.63)d,(7.26±0.35)d and(5.35±0.43)d in the control group,the differences between the groups were statistically significant(P<0.05).After treatment,the levels of various pulmonary function indexes in the observation group were better than those in the control group,and the differences between the groups were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Salbutamol combined with budesonide is effective in the treatment of children with bronchial asthma,which can accelerate the regression of symptoms and improve pulmonary function.
作者
刘晓瑜
钱佳佳
LIU Xiaoyu;QIAN Jiajia(Department of Pediatrics,Weihai Central Hospital,Weihai Shandong,264400,China;Department of Pharmacy,Weihai Central Hospital,Weihai Shandong,264400,China)
出处
《反射疗法与康复医学》
2023年第4期123-125,141,共4页
Reflexology And Rehabilitation Medicine
关键词
支气管哮喘
沙丁胺醇
布地奈德
临床疗效
症状消失时间
复发
肺功能
不良反应
Bronchial asthma
Salbutamol
Budesonide
Clinical efficacy
Symptom disappearance time
Recurrence
Pulmonary function
Adverse reactions
