摘要
目的探讨玻璃酸钠滴眼液与小牛血去蛋白提取物滴眼液联合应用于白内障术后患者中的效果.方法选取该院2021年10月—2022年8月收治的120例白内障术后患者为研究对象,按随机数字表法分为两组,对照组(n=60)用常规滴眼药物,观察组(n=60)在对照组基础上加用小牛血去蛋白提取物滴眼液与玻璃酸钠滴眼液.对比两组干眼症状、角膜荧光素染色(FL)评分、泪膜破裂时间(BUT)、视觉质量及并发症发生率.结果术前,两组眼表疾病指数量表(OSDI)评分、FL评分、BUT、斯特列尔比(SR)、客观散射指数(OSI)、调制传递函数截止频率(MTF cut-off)比较,组间差异无统计学意义(P>0.05);术后,观察组的OSDI评分(6.44±1.07)分、FL评分(0.64±0.14)分、OSI(1.12±0.43)均低于对照组的(10.14±2.28)分、(1.23±0.24)分、(2.03±0.66),BUT(13.45±2.02)s长于对照组的(10.17±1.74)s,MTF cut-off(34.66±5.14)lp/mm、SR(0.17±0.03)均高于对照组的(21.37±6.17)lp/mm、(0.12±0.02),并发症发生率3.33%低于对照组的13.33%,组间差异有统计学意义(P<0.05).结论小牛血去蛋白提取物滴眼液与玻璃酸钠滴眼液联合应用在白内障术后患者中效果显著,能够缓解眼部不适,减轻干眼症状,降低并发症发生率,提高视觉质量.
Objective To investigate the effect of sodium hyaluronate eye drops combined with calf blood deproteinized extract eye drops in patients after cataract surgery.Methods 120 patients after cataract surgery admitted to the hospital from October 2021 to August 2022 were selected as the research objects and divided into two groups according to the method of random number table.The control group(n=60)was treated with conventional eye drops,and the observation group(n=60)was treated with calf blood deproteinized extract eye drops and sodium hyaluronate eye drops on the basis of the control group.The dry eye symptoms,corneal fluorescein staining(FL)score,tear film break up time(BUT),visual quality and the incidence of complications were compared between the two groups.Results Before surgery,there were no significant differences in ocular surface disease index(OSDI)score,FL score,BUT,strehl ratio(SR),object scatter index(OSI)and modulation transfer function cut-off frequency(MTF cut-off)between the two groups(P>0.05);after treatment,the OSDI score(6.44±1.07)points,FL score(0.64±0.14)points and OSI(1.12±0.43)of the observation group were lower than(10.14±2.28)points,(1.23±0.24)points and(2.03±0.66)of the control group,and the BUT(13.45±2.02)s was longer than(10.17±1.74)s of the control group,MTF cut-off(34.66±5.14)lp/mm and SR(0.17±0.03)of the observation group were higher than(21.37±6.17)lp/mm and(0.12±0.02)of the control group,respectively,the incidence of complications 3.33%was lower than 13.33%of the control group(P<0.05).Conclusion The combination of calf blood deproteinized extract eye drops and sodium hyaluronate eye drops has a better effect in patients after cataract surgery.It can relieve eye discomfort,alleviate dry eye symptoms,reduce the incidence of complications,and improve visual quality.
作者
王亚军
郭春凤
WANG Yajun;GUO Chunfeng(Department of Ophthalmology,Juye County People's Hospital,Shandong Province,Heze Shandong,274900,China)
出处
《反射疗法与康复医学》
2023年第4期119-122,共4页
Reflexology And Rehabilitation Medicine
关键词
白内障
小牛血去蛋白提取物滴眼液
玻璃酸钠滴眼液
干眼症
视觉质量
Cataract
Calf blood deproteinized extract eye drops
Sodium hyaluronate eye drops
Xerophthalmia
Visual quality
