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生物反馈联合莫沙必利对慢性功能性便秘患者肛门及直肠肌肉协调性、临床症状的影响

Effect of Biofeedback Combined with Moxapride on Anal and Rectal Muscle Coordination and Clinical Symptoms in Patients with Chronic Functional Constipation
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摘要 目的探讨生物反馈联合莫沙必利在慢性功能性便秘(FC)患者中的应用效果.方法选取2021年4月—2022年3月我院收治的FC患者92例,按随机数字表法分为两组,对照组46例采用莫沙必利片治疗,观察组46例在对照组基础上采用生物反馈治疗,均持续12周.对比两组患者的临床疗效、肛门及直肠肌肉协调性与临床症状积分.结果治疗后,观察组的治疗总有效率为97.83%,显著高于对照组的82.61%,差异有统计学意义(P<0.05).治疗后,观察组的肛管收缩压、肛管静息压、直肠肛管压力差均高于对照组,力排时肛管残余压、各项临床症状积分均低于对照组,组间差异有统计学意义(P<0.05).结论生物反馈联合莫沙必利治疗FC的效果显著,能改善患者肛门及直肠肌肉协调性,减轻临床症状,且安全性高. Objective To investigate the effect of biofeedback combined with moxapride in patients with chronic functional constipation(FC).Methods A total of 92 patients with FC admitted to our hospital from April 2021 to March 2022 were divided into two groups according to random number table method.The control group of 46 cases was treated with moxapride tablets,and the observation group of 46 cases was treated with biofeedback based on the control group.Both groups lasted for 12 weeks.The clinical efficacy,anal and rectal muscle coordination and clinical symptom score were compared between the two groups.Results After treatment,the total effective rate of the observation group was 97.83%,which was significantly higher than 82.61%of the control group,the difference was statistically significant(P<0.05).After treatment,the anal systolic blood pressure,anal resting pressure and rectal anal pressure difference in the observation group were higher than those in the control group,while the anal residual pressure and clinical symptom scores in the discharge group were lower than those in the control group,the differences between the groups were statistically significant(P<0.05).Conclusion Biofeedback combined with moxapride has a significant effect in the treatment of FC,which can improve the anal and rectal muscle coordination of patients and alleviate clinical symptoms,with high safety.
作者 管振安 GUAN Zhen'an(Department of Proctology,Liaocheng Dongchangfu District Hospital of Traditional Chinese Medicine,Liaocheng Shandong,252000,China)
出处 《反射疗法与康复医学》 2022年第22期83-86,共4页 Reflexology And Rehabilitation Medicine
关键词 慢性功能性便秘 生物反馈 莫沙必利 临床症状 Chronic functional constipation Biofeedback Moxapride Clinical symptoms
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