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益肾降压汤对原发性高血压患者中医证候、血压水平及生活质量的影响

Effect of Yishen Jiangya Decoction on TCM Syndrome,Blood Pressure Level and Quality of Life of Patients with Primary Hypertension
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摘要 目的探究益肾降压汤对原发性高血压患者中医证候、血压水平及生活质量的影响.方法选择本院2020年12月—2022年3月收治的86例原发性高血压患者,按随机数字表法分为对照组43例和观察组43例.对照组采用常规治疗,观察组在此基础上采用益肾降压汤治疗,均持续治疗1个月.比较两组的治疗效果.结果观察组的治疗总有效率为95.35%,高于对照组的79.07%,差异有统计学意义(P<0.05).治疗后,观察组的中医证候积分及舒张压、收缩压水平均低于对照组,组间差异有统计学意义(P<0.05).治疗后,观察组生活质量综合评定问卷中的躯体功能、心理功能、社会功能、物质生活状态评分分别为(76.15±5.29)分、(72.32±6.21)分、(75.85±5.46)分、(78.43±5.38)分,均高于对照组,组间差异有统计学意义(P<0.05).两组部分患者出现轻微不良反应,未给予任何对症治疗,停药后自行消失,均未出现较严重的不良反应.结论采用益肾降压汤治疗原发性高血压患者可有效减轻中医证候,降低血压水平,改善生活质量,且安全可靠. Objective To explore the effect of Yishen Jiangya Decoction on TCM syndrome,blood pressure level and quality of life of patients with primary hypertension.Methods A total of 86 patients with primary hypertension admitted to the hospital from December 2020 to March 2022 were selected and were divided into a control group of 43 cases and an observation group of 43 cases according to the random number table method.The control group was treated with conventional treatment,and the observation group was treated with Yishen Jiangya Decoction on this basis.Both groups were treated for 1 month.The treatment effects of the two groups were compared.Results The total effective rate of the observation group was 95.35%,which was higher than 79.07%of the control group,and the difference was statistically significant(P<0.05).After treatment,the TCM syndrome score,diastolic blood pressure and systolic blood pressure of the observation group were lower than those of the control group,and the differences between the groups were statistically significant(P<0.05).After treatment,the scores of physical function,psychological function,social function and material life status in generic quality of life inventory-74 in the observation group were(76.15±5.29)points,(72.32±6.21)points,(75.85±5.46)points and(78.43±5.38)points,which were higher than those in the control group,the differences between the groups were statistically significant(P<0.05).Some patients in the two groups had mild adverse reactions,which were not given any symptomatic treatment and disappeared spontaneously after drug withdrawal.There were no serious adverse reactions in the two groups.Conclusion Yishen Jiangya Decoction is safe and reliable in the treatment of patients with primary hypertension.It can effectively reduce TCM syndrome,reduce blood pressure level and improve quality of life.
作者 徐金红 XU Jinhong(Department of Pharmacy,Chiping District Second People's Hospital,Liaocheng Shandong,252111,China)
出处 《反射疗法与康复医学》 2022年第19期62-65,共4页 Reflexology And Rehabilitation Medicine
关键词 原发性高血压 益肾降压汤 中医证候 血压 生活质量 Primary hypertension Yishen Jiangya Decoction TCM syndromes Blood pressure Quality of life
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