摘要
目的分析康复新液联合兰索拉唑胶囊治疗消化性溃疡的临床疗效.方法纳入2020年1月—2022年1月本院收治的165例消化性溃疡患者,按照用药方案的不同分为治疗组(n=83)与对照组(n=82).对照组采用兰索拉唑胶囊治疗,治疗组在对照组基础上加用康复新液治疗,均治疗4周.比较两组临床疗效、胃酸pH、血清胃泌素水平及药品不良反应情况.结果服药4周后,治疗组总有效率显著高于对照组,差异有统计学意义(P<0.05);两组患者服药4周后胃液pH均显著高于治疗前,血清胃泌素水平均显著低于治疗前,且治疗组胃液pH显著高于对照组,血清胃泌素水平显著低于对照组,组间差异有统计学意义(P<0.05);服药期间,两组患者药品不良反应发生率比较,差异无统计学意义(P>0.05).结论康复新液联合兰索拉唑胶囊治疗消化性溃疡可取得显著疗效,且安全性良好,治疗后患者胃酸pH增高,血清胃泌素水平降低.
Objective To analyze the clinical efficacy of kangfuxin fluid combined with lansoprazole capsule in the treatment of peptic ulcer.Methods A total of 165 patients admitted to the hospital from January 2020 to January 2022 were included in this study,and they were divided into the treatment group(n=83)and the control group(n=82)according to the different medication regimen.The control group was treated with lansoprazole capsule,and the treatment group was treated with kangfuxin fluid on the basis of the control group,with both interventions for 4 weeks.The clinical efficacy,gastric acid pH,serum gastrin level and adverse drug reactions were compared.Results After taking the medicine for 4 weeks,the total effective rate of the treatment group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05);the pH of gastric juice in the two groups after taking the medicine for 4 weeks were significantly higher than those before treatment,the level of serum gastrin were significantly lower than those before treatment,and the pH of gastric juice in the treatment group was significantly higher than that in the control group,the level of serum gastrin was significantly lower than that in the control group,the differences between the groups were statistically significant(P<0.05);during the period of taking the medicine,there was no significant difference in the incidence of adverse drug reactions(P>0.05).Conclusion Kangfuxin fluid combined with lansoprazole capsule can achieve significant curative effect in treatment of peptic ulcer,with good safety.After treatment,the pH of gastric acid increases and serum gastrin level decreases.
作者
叶欣
李煊
YE Xin;LI Xuan(Department of Gastroenterology,Xuyi County People's Hospital,Huai'an,Jiangsu Province,Huai'an Jiangsu,211700,China)
出处
《反射疗法与康复医学》
2022年第13期140-142,共3页
Reflexology And Rehabilitation Medicine
