摘要
目的探讨全视网膜激光光凝(PRP)联合复合式小梁切除术及康柏西普在新生血管性青光眼(NVG)患者中的应用效果.方法选取本院2017年12月—2021年9月收治的82例NVG患者,按随机数字表法分为两组,每组41例.对照组行PRP联合复合式小梁切除术,观察组在此基础上加用康柏西普,均观察至术后3个月.对比两组的临床疗效、视力、眼压及并发症发生率.结果观察组的治疗总有效率为92.68%,高于对照组的75.61%,差异有统计学意义(P<0.05).术前,两组的最佳矫正视力(BCVA)及眼压比较,组间差异无统计学意义(P>0.05);术后3个月,观察组的BCVA高于对照组,眼压低于对照组,组间差异有统计学意义(P<0.05).观察组的并发症发生率为4.88%,低于对照组的19.51%,差异有统计学意义(P<0.05).结论PRP联合复式小梁切除术及康柏西普在NVG治疗中的效果确切,能够显著降低患者眼压,提升视力,且并发症较少,值得应用.
Objective To investigate the effect of pan-retinal photocoagulation(PRP)combined with compound trabeculectomy and conbercept in patients with neovascular glaucoma(NVG).Methods A total of 82 NVG patients admitted to our hospital from December 2017 to September 2021 were selected and divided into two groups according to the random number table method,with 41 cases in each group.The control group was treated with PRP combined with compound trabeculectomy,and the observation group was treated with conbercept on this basis,both groups were observed until 3 months after operation.The clinical efficacy,visual acuity,intraocular pressure and incidence of complications were compared between the two groups.Results The total effective rate of observation group was 92.68%,higher than 75.61%of control group,the difference was statistically significant(P<0.05).Before surgery,there were no significant difference in best corrected visual acuity(BCVA)and intraocular pressure between the two groups(P>0.05);3 months after surgery,the BCVA in the observation group was higher than that in the control group,and the intraocular pressure in the observation group was lower than that in the control group,the differences between the groups were statistically significant(P<0.05).The incidence of complications in the observation group was 4.88%,lower than 19.51%in the control group,and the difference was statistically significant(P<0.05).Conclusion PRP combined with compound trabeculectomy and conbercept has a definite effect in the treatment of NVG,can significantly reduce intraocular pressure and improve visual acuity,and has fewer complications,which is worthy of application.
作者
张淑燕
ZHANG Shuyan(Department of Ophthalmology,Rizhao People's Hospital,Rizhao Shandong,276800,China)
出处
《反射疗法与康复医学》
2022年第11期93-95,共3页
Reflexology And Rehabilitation Medicine
