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奥美拉唑联合替普瑞酮治疗老年慢性浅表性胃炎患者的临床效果及对其临床症状、胃肠激素水平的影响 被引量:2

Clinical Effect of Omeprazole Combined with Tepreone in the Treatment of Elderly Patients with Chronic Superficial Gastritis and Its Influence on Clinical Symptoms and Gastrointestinal Hormone Levels
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摘要 目的探究奥美拉唑联合替普瑞酮在老年慢性浅表性胃炎患者中的应用效果.方法选取该院2020年7月—2022年3月收治的92例老年慢性浅表性胃炎患者为研究对象,根据门诊就诊序号单双数分组,将单数者纳入对照组(n=46),将双数者纳入研究组(n=46).对照组采用奥美拉唑治疗,研究组在对照组基础上联合采用替普瑞酮治疗.比较两组治疗总有效率、治疗前后临床症状和胃肠激素水平.结果与对照组比较,研究组治疗总有效率较高,差异有统计学意义(P<0.05).治疗8周后,与对照组相比,研究组临床症状评分、生长抑素水平均较低,胃泌素、胃动素水平均较高,组间差异有统计学意义(P<0.05).结论老年慢性浅表性胃炎患者采用奥美拉唑联合替普瑞酮治疗,可提高疗效,促进其临床症状改善和胃肠功能康复. Objective To explore the application effect of omeprazole combined with tepreone in elderly patients with chronic superficial gastritis.Methods 92 elderly patients with chronic superficial gastritis admitted to the hospital from July 2020 to March 2022 were selected as the research objects,according to the odd-even number of outpatient visits,the oddnumbered patients were included in the control group(n=46),and the even-numbered patients were included in the study group(n=46).The control group was treated with omeprazole,and the study group was treated with tepreone on the basis of the control group.The total effective rate,clinical symptoms and gastrointestinal hormone levels before and after treatment were compared between the two groups.Results Compared with the control group,the total effective rate of the study group was higher,and the difference was statistically significant(P<0.05).After 8 weeks of treatment,compared with the control group,the clinical symptom scores and the levels of somatostatin in the study group were lower,the levels of gastrin and motilin in the study group were higher,and the differences between the groups were statistically significant(P<0.05).Conclusion Omeprazole combined with tepreone in the treatment of elderly patients with chronic superficial gastritis can improve the curative effect,promote the improvement of clinical symptoms and the rehabilitation of gastrointestinal function.
作者 张永和 ZHANG Yonghe(Department of Gastroenterology,Zhangye Second People's Hospital,Gansu Province,Zhangye Gansu,734000,China)
出处 《反射疗法与康复医学》 2022年第17期130-132,共3页 Reflexology And Rehabilitation Medicine
关键词 慢性浅表性胃炎 老年 奥美拉唑 替普瑞酮 胃肠功能 Chronic superficial gastritis Old age Omeprazole Tepredone Gastrointestinal function
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