摘要
目的研究舒肝消癖颗粒与复方甘草酸苷片联合治疗对非酒精性脂肪肝(NAFLD)患者的影响.方法选择2020年4月—2021年8月我院收治的NAFLD患者100例,采用随机数字表法分为两组,每组50例.对照组采用复方甘草酸苷片治疗,观察组在对照组基础上采用舒肝消癖颗粒治疗,两组均治疗3个月.对比两组的临床疗效、天冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、谷氨酰转肽酶(GGT)水平及高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)、总胆固醇(TC)水平.结果观察组的治疗总有效率为94.00%,高于对照组的80.00%,差异有统计学意义(P<0.05).治疗后,观察组的AST、ALT、GGT、TG、TC、LDL-C水平均低于对照组,HDL-C水平高于对照组,组间差异有统计学意义(P<0.05).结论NAFLD患者采用复方甘草酸苷片联合舒肝消癖颗粒治疗可获得确切疗效,可改善其血脂水平及肝功能,值得临床推广使用.
Objective To study the effect of Shugan Xiaopi Granule combined with compound glycyrrhizin tablets on patients with nonalcoholic fatty liver disease(NAFLD).Methods A total of 100 NAFLD patients admitted to our hospital from April 2020 to August 2021 were selected and divided into two groups by random number table method,with 50 patients in each group.The control group was treated with compound glycyrrhizin tablets,and the observation group was treated with Shugan Xiaopi Granules on the basis of the control group.Both groups were treated for 3 months.The clinical curative effect and the levels of aspartate aminotransferase(AST),alanine aminotransferase(ALT),γ-glutamyl transpeptadase(GGT),the levels of high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),triglyceride(TG),total cholesterol(TC)were compared between the two groups.Results The total effective rate of the observation group was94.00%,higher than 80.00%of the control group,the difference was statistically significant(P<0.05).After treatment,the AST,ALT,GGT,TG,TC and LDL-C levels in the observation group were lower than those in the control group,while HDL-C level was higher than that in the control group,the differences between the groups were statistically significant(P<0.05).Conclusion The treatment of NAFLD patients with compound glycyrrhizin tablets combined with Shugan Xiaopi Granules can obtain a definite curative effect,improve the level of blood lipid and liver function,and is worthy of clinical application.
作者
李斌
王磊
LI Bin;WANG Lei(Department of Hepatobiliary Medicine,Zaozhuang Hospital,Beijing University of Traditional Chinese Medicine(Zaozhuang Traditional Chinese Medicine Hospital),Zaozhuang Shandong,277000,China)
出处
《反射疗法与康复医学》
2022年第7期8-10,共3页
Reflexology And Rehabilitation Medicine
关键词
非酒精性脂肪肝
舒肝消癖颗粒
复方甘草酸苷片
肝功能
血脂
Nonalcoholic fatty liver disease
Shugan Xiaopi Granule
Compound glycyrrhizin tablets
Liver function
Blood lipid
